Metoprolol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms / Brand Names: Lopressor, Toprol XL, Toprolxl XL

Overview

Metoprolol is a competitive, β1-selective (cardioselective) blocker used in treatment of angina pectoris, hypertension, arrhythmia, and migraine. Common adverse reactions include bradyarrhythmia, heart block, heart failure, hypotension, pruritus, rash, constipation, diarrhea, indigestion, nausea, dizziness, fatigue, headache, depression, dyspnea, and wheezing.

The active substance metoprolol is employed either as metoprolol succinate or as metoprolol tartrate (where 100 mg metoprolol tartrate corresponds to 95 mg metoprolol succinate). The tartrate is an immediate-release and the succinate is an extended-release formulation.[1]

Category

Anti-anginal, antiarrhythmic, beta-adrenergic blocker

Prescribing Information

Metoprolol Succinate

Metoprolol Succinate/Hydrochlorothiazide

Dutoprol

Metoprolol Tartrate

Lopressor

Metoprolol Tartrate/Arginine

Hypertensolol

Metoprolol Tartrate/Hydrochlorothiazide

Lopressor HCT

References

  1. Cupp M (2009). "Alternatives for Metoprolol Succinate" (pdf). Pharmacist's Letter / Prescriber's Letter. 25 (250302).