Metopon

Revision as of 19:34, 4 September 2012 by WikiBot (talk | contribs) (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Metopon
160px
Clinical data
SynonymsMetopon, 5β-methyl-7,8-dihydromorphin-6-one
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC18H21NO3
Molar mass299.364 g/mol

Metopon (5-methylhydromorphone hydrochloride) is an opiate analogue that is a methylated derivative of hydromorphone which was invented in 1948 as an analgesic. [1]

Metopon is sometimes used in medicine, but although longer acting than hydromorphone, metopon is less potent and has poor oral bioavailability, so generally has few advantages to distinguish it from other, more commonly used opioid analgesics. [2] It has similar side effects to other opiates, which include itching, nausea and respiratory depression.


CAS number 124-92-5 (Metopon hydrochloride)

References

  1. Eddy NB. Pharmacology of Metopon and other new analgesic opium derivatives. Annals of the New York Academy of Sciences. 1948; 51(1):51–58.
  2. McLaughlin JP, Nowak D, Sebastian A, Schultz AG, Archer S, Bidlack JM. Metopon and two unique derivatives: affinity and selectivity for the multiple opioid receptors. European Journal of Pharmacology. 1995 Dec 27;294(1):201-6.

sv:Metopon


Linked-in.jpg