Metaclazepam

Metaclazepam
	File:Metaclazepam.svg
Identifiers
	IUPAC name 7-bromo-5-(2-chlorophenyl)-2-(methoxymethyl) -1-methyl-2,3-dihydro-1,4-benzodiazepine;
CAS Number	84031-17-4;
PubChem CID	71272;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C18H18BrClN2O
Molar mass	393.705

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

Metaclazepam (Talis) is a drug which is a benzodiazepine derivative. It is a relatively selective anxiolytic with less sedative or muscle relaxant properties than other benzodiazepines such as diazepam or bromazepam.^[1]

Metaclazepam is slightly more effective as an anxiolytic than bromazepam,^[2] or diazepam,^[3] with a 15mg dose of metaclazepam equivalent to 4mg of bromazepam.^[4]

Template:Pharma-stub

References

↑ Buschmann G, Kuhl UG, Rohte O. General pharmacology of the anxiolytic compound metaclazepam in comparison to other benzodiazepines. Arzneimittelforschung. 1985;35(11):1643-55.
↑ Bilone F, Roncari R. A double-blind comparison of the anxiolytic activity of two benzodiazepines, metaclazepam and bromazepam, in anxiety neurosis. Current Medical Research and Opinion. 1988;11(1):45-7.
↑ Laakmann G, Blaschke D, Hippius H, Schewe S. Double-blind study of metaclazepam versus diazepam treatment of outpatients with anxiety syndrome. Pharmacopsychiatry. 1989 May;22(3):120-5.
↑ Marano P, Patti F, Nicoletti F. Controlled study on the anxiolytic activity of a newly-developed benzodiazepine, metaclazepam. Current Medical Research and Opinion. 1988;11(1):41-4.

Template:Benzodiazepines Template:WikiDoc Sources

[1] Buschmann G, Kuhl UG, Rohte O. General pharmacology of the anxiolytic compound metaclazepam in comparison to other benzodiazepines. Arzneimittelforschung. 1985;35(11):1643-55.

[2] Bilone F, Roncari R. A double-blind comparison of the anxiolytic activity of two benzodiazepines, metaclazepam and bromazepam, in anxiety neurosis. Current Medical Research and Opinion. 1988;11(1):45-7.

[3] Laakmann G, Blaschke D, Hippius H, Schewe S. Double-blind study of metaclazepam versus diazepam treatment of outpatients with anxiety syndrome. Pharmacopsychiatry. 1989 May;22(3):120-5.

[4] Marano P, Patti F, Nicoletti F. Controlled study on the anxiolytic activity of a newly-developed benzodiazepine, metaclazepam. Current Medical Research and Opinion. 1988;11(1):41-4.

[1]

[2]

[3]

[4]

Identifiers
File:Metaclazepam.svg
IUPAC name 7-bromo-5-(2-chlorophenyl)-2-(methoxymethyl) -1-methyl-2,3-dihydro-1,4-benzodiazepine
CAS Number	84031-17-4
PubChem CID	71272
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₈H₁₈BrClN₂O
Molar mass	393.705

Metaclazepam

References

Navigation menu