Meningococcemia natural history, complications and prognosis
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Meningococcemia Microchapters |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
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Complications
Patients who do not develop meningitis also tend to have a poorer outcome.
- Arthritis
- Disseminated intravascular coagulopathy (DIC)
- Gangrene due to lack of blood supply
- In cases of serious infection, sufferers may have to have limbs amputated as infected flesh dies off and may otherwise spread gangrene.
- Inflammation of blood vessels in the skin (cutaneous vasculitis).
- Myocarditis
- Pericarditis
- Shock
- Severe damage to adrenal glands that can lead to low blood pressure (Waterhouse-Friderichsen syndrome).
Prognosis
Early treatment results in a good outcome. When shock develops, the outcome is less certain. The condition is most life threatening in those who have:
- Disseminated intravascular coagulopathy (DIC) - a severe bleeding disorder
- Kidney failure
- Shock