Mast cell leukemia natural history, complications, and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, | If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.<ref name="JorisGeorgin-Lavialle2012" /> Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012" /> | ||
Common complications of | |||
Prognosis is generally | |||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.<ref name="JorisGeorgin-Lavialle2012">{{cite journal|last1=Joris|first1=Magalie|last2=Georgin-Lavialle|first2=Sophie|last3=Chandesris|first3=Marie-Olivia|last4=Lhermitte|first4=Ludovic|last5=Claisse|first5=Jean-François|last6=Canioni|first6=Danielle|last7=Hanssens|first7=Katia|last8=Damaj|first8=Gandhi|last9=Hermine|first9=Olivier|last10=Hamidou|first10=Mohammed|title=Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive|journal=Case Reports in Hematology|volume=2012|year=2012|pages=1–6|issn=2090-6560|doi=10.1155/2012/517546}}</ref> Prognosis is generally poor, and the median survival time is less than six months. | If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.<ref name="JorisGeorgin-Lavialle2012">{{cite journal|last1=Joris|first1=Magalie|last2=Georgin-Lavialle|first2=Sophie|last3=Chandesris|first3=Marie-Olivia|last4=Lhermitte|first4=Ludovic|last5=Claisse|first5=Jean-François|last6=Canioni|first6=Danielle|last7=Hanssens|first7=Katia|last8=Damaj|first8=Gandhi|last9=Hermine|first9=Olivier|last10=Hamidou|first10=Mohammed|title=Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive|journal=Case Reports in Hematology|volume=2012|year=2012|pages=1–6|issn=2090-6560|doi=10.1155/2012/517546}}</ref> Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
==References== | ==References== |
Latest revision as of 20:39, 22 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]
Natural History, Complications, and Prognosis
If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]
References
- ↑ 1.0 1.1 Joris, Magalie; Georgin-Lavialle, Sophie; Chandesris, Marie-Olivia; Lhermitte, Ludovic; Claisse, Jean-François; Canioni, Danielle; Hanssens, Katia; Damaj, Gandhi; Hermine, Olivier; Hamidou, Mohammed (2012). "Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive". Case Reports in Hematology. 2012: 1–6. doi:10.1155/2012/517546. ISSN 2090-6560.
- ↑ 2.0 2.1 Georgin-Lavialle, S.; Lhermitte, L.; Dubreuil, P.; Chandesris, M.-O.; Hermine, O.; Damaj, G. (2012). "Mast cell leukemia". Blood. 121 (8): 1285–1295. doi:10.1182/blood-2012-07-442400. ISSN 0006-4971.