Malignant peripheral nerve sheath tumor medical therapy: Difference between revisions

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==Treatment==
==Treatment==
The first-line treatment is surgical resection with wide margins. [[Chemotherapy]] (e.g. high-dose [[doxorubicin]]) and often [[radiation therapy|radiotherapy]] are done as adjuvant and/or neoadjuvant treatment.
'''Radiation'''<ref>Malignant peripheral nerve sheath tumor. Wikipedia 2015. https://en.wikipedia.org/wiki/Malignant_peripheral_nerve_sheath_tumor#cite_note-Valeyrie-Allanore_2005_79-4</ref>
Treatment for neurofibrosarcoma is similar to that of other cancers.
* [[Radiation]] will be used in conjunction with surgery, especially if the limb was not amputated. Radiation is rarely used as a sole treatment.
Surgery is an option; the removal of the tumor along with surrounding tissue may be vital for the patient’s survival. For discrete, localized tumors, surgery is often followed by [[radiation]] therapy of the excised area to reduce the chance of recurrence.
 
For patients suffering from neurofibrosarcomas in an extremity, if the tumor is vascularized (has its own blood supply) and has many nerves going through it and/or around it, amputation of the extremity may be necessary. Some surgeons argue that amputation should be the procedure of choice when possible, due to the increased chance of a better quality of life. Otherwise, surgeons may opt for a limb-saving treatment, by removing less of the surrounding tissue or part of the bone, which is replaced by a metal rod or grafts.
'''Chemotherapy'''
[[Radiation]] will also be used in conjunction with surgery, especially if the limb was not amputated. Radiation is rarely used as a sole treatment.
* In some instances, the oncologist may choose [[chemotherapy]] drugs when treating a patient with neurofibrosarcoma, usually in conjunction with surgery. Patients taking chemotherapy must be prepared for the [[side effects]] that come with any other chemotherapy treatment, such as hair loss, lethargy, [[weakness]], etc.
In some instances, the oncologist may choose [[chemotherapy]] drugs when treating a patient with neurofibrosarcoma, usually in conjunction with surgery. Patients taking chemotherapy must be prepared for the side effects that come with any other chemotherapy treatment, such as; hair loss, lethargy, weakness, etc.


==References==
==References==
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[[Category:Neurology]]

Revision as of 17:06, 7 December 2015

Malignant peripheral nerve sheath tumor Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]

Overview

The predominant therapy for malignant peripheral nerve sheath tumor is surgical resection. Adjunctive chemotherapy and radiation therapy may be required.

Treatment

Radiation[1]

  • Radiation will be used in conjunction with surgery, especially if the limb was not amputated. Radiation is rarely used as a sole treatment.

Chemotherapy

  • In some instances, the oncologist may choose chemotherapy drugs when treating a patient with neurofibrosarcoma, usually in conjunction with surgery. Patients taking chemotherapy must be prepared for the side effects that come with any other chemotherapy treatment, such as hair loss, lethargy, weakness, etc.

References

  1. ↑ Malignant peripheral nerve sheath tumor. Wikipedia 2015. https://en.wikipedia.org/wiki/Malignant_peripheral_nerve_sheath_tumor#cite_note-Valeyrie-Allanore_2005_79-4

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