Malabsorption other diagnostic studies: Difference between revisions
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[[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | [[Image:Coeliac path.jpg|thumb|left|Biopsy of [[small bowel]] showing coeliac disease manifested by blunting of [[villi]], crypt hyperplasia, and [[lymphocyte]] infiltration of crypts.]] | ||
*Endoscopy is frequently undertaken, but to visualise small intestine which can be up to 7m long is indeed a daunting task. | *Endoscopy is frequently undertaken, but to visualise small intestine which can be up to 7m long is indeed a daunting task. | ||
:[[OGD]] to reveal duodenal lesion also for D2 biopsy (for celiac disease, tropical sprue, Whipple disease, A-b-lipoproteinemia etc.) | :*[[OGD]] to reveal duodenal lesion also for D2 biopsy (for celiac disease, tropical sprue, Whipple disease, A-b-lipoproteinemia etc.) | ||
:[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth | :*[[Enteroscopy]] for enteropathy and jejunal aspirate and culture for bacterial overgrowth | ||
:[[Colonoscopy]] is helpful in colonic or ileal lesion. | :*[[Colonoscopy]] is helpful in colonic or ileal lesion. | ||
*[[ERCP]] | *[[ERCP]] | ||
Revision as of 18:34, 30 November 2012
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Malabsorption |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Other Diagnostic Studies
Radiological Studies
- Barium follow through is useful in delineating small intestinal anatomy. Barium enema may be undertaken to see colonic or ileal lesions.
- CT abdomen is useful in ruling out structural abnormality, done in pancreatic protocol when visualising pancreas.
- MRCP to complement or as an alternative to ERCP
Interventional Studies
- Endoscopy is frequently undertaken, but to visualise small intestine which can be up to 7m long is indeed a daunting task.
- OGD to reveal duodenal lesion also for D2 biopsy (for celiac disease, tropical sprue, Whipple disease, A-b-lipoproteinemia etc.)
- Enteroscopy for enteropathy and jejunal aspirate and culture for bacterial overgrowth
- Colonoscopy is helpful in colonic or ileal lesion.
Other Investigations
- Radio isotope tests e.g. 75SeHCAT, 95mTc to exclude terminal ileal disease.
- Sugar probes or sub 51Cr-EDTA to determine intestinal permeability[1].
- Glucose hydrogen breath test for bacterial overgrowth
- D-xylose absorption test. lower level in urine after ingestion indicates bacterial overgrowth or reduced absorptive surface. normal in pancreatic insufficiency.
- Bile salt breath test to determine bile salt malabsorption.
- Schilling test to establish cause of B12 deficiency.
- Lactose H2 breath test for lactose intolerance