MT1E: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Underlinked|date=March 2014}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{Infobox_gene}}
{{GNF_Protein_box
'''Metallothionein-1E''' is a [[protein]] that in humans is encoded by the ''MT1E'' [[gene]].<ref name="pmid6089206">{{cite journal |vauthors=Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB | title = Human metallothionein genes are clustered on chromosome 16 | journal = Proc Natl Acad Sci U S A | volume = 81 | issue = 17 | pages = 5494–8 |date=Oct 1984 | pmid = 6089206 | pmc = 391732 | doi =10.1073/pnas.81.17.5494 }}</ref><ref name="pmid2581970">{{cite journal |vauthors=Schmidt CJ, Jubier MF, Hamer DH | title = Structure and expression of two human metallothionein-I isoform genes and a related pseudogene | journal = J Biol Chem | volume = 260 | issue = 12 | pages = 7731–7 |date=Jul 1985 | pmid = 2581970 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MT1E metallothionein 1E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4493| accessdate = }}</ref>
| image = PBB_Protein_MT1E_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1mhu.
| PDB = {{PDB2|1mhu}}, {{PDB2|1mrb}}, {{PDB2|2mhu}}, {{PDB2|2mrt}}
| Name = Metallothionein 1E
| HGNCid = 7397
| Symbol = MT1E
| AltSymbols =; MT1; MTD
| OMIM = 156351
| ECnumber =
| Homologene = 81614
| MGIid = 97171
| GeneAtlas_image1 = PBB_GE_MT1E_212859_x_at_tn.png
  | Function = {{GNF_GO|id=GO:0005507 |text = copper ion binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046870 |text = cadmium ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
| Process = {{GNF_GO|id=GO:0008150 |text = biological_process}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4493
    | Hs_Ensembl = ENSG00000169715
    | Hs_RefseqProtein = NP_783316
    | Hs_RefseqmRNA = NM_175617
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 55216888
    | Hs_GenLoc_end = 55218525
    | Hs_Uniprot = P04732
    | Mm_EntrezGene = 17748
    | Mm_Ensembl = ENSMUSG00000031765
    | Mm_RefseqmRNA = NM_013602
    | Mm_RefseqProtein = NP_038630
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 97068356
    | Mm_GenLoc_end = 97069453
    | Mm_Uniprot = P02802
  }}
}}
'''Metallothionein 1E''', also known as '''MT1E''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MT1E metallothionein 1E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4493| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 55: Line 11:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=West AK, Stallings R, Hildebrand CE, ''et al.'' |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513-8 |year= 1991 |pmid= 2286373 |doi= }}
*{{cite journal   |vauthors=West AK, Stallings R, Hildebrand CE, etal |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513–8 |year= 1991 |pmid= 2286373 |doi=10.1016/0888-7543(90)90038-V }}
*{{cite journal  | author=Schmidt CJ, Jubier MF, Hamer DH |title=Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. |journal=J. Biol. Chem. |volume=260 |issue= 12 |pages= 7731-7 |year= 1985 |pmid= 2581970 |doi= }}
*{{cite journal  |vauthors=Le Beau MM, Diaz MO, Karin M, Rowley JD |title=Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. |journal=Nature |volume=313 |issue= 6004 |pages= 709–11 |year= 1985 |pmid= 3856101 |doi=10.1038/313709a0 }}
*{{cite journal  | author=Le Beau MM, Diaz MO, Karin M, Rowley JD |title=Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. |journal=Nature |volume=313 |issue= 6004 |pages= 709-11 |year= 1985 |pmid= 3856101 |doi= }}
*{{cite journal   |vauthors=Carter AD, Felber BK, Walling MJ, etal |title=Duplicated heavy metal control sequences of the mouse metallothionein-I gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 23 |pages= 7392–6 |year= 1985 |pmid= 6095291 |doi=10.1073/pnas.81.23.7392  | pmc=392152 }}
*{{cite journal  | author=Karin M, Eddy RL, Henry WM, ''et al.'' |title=Human metallothionein genes are clustered on chromosome 16. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 17 |pages= 5494-8 |year= 1984 |pmid= 6089206 |doi= }}
*{{cite journal  |vauthors=Kondo Y, Kuo SM, Lazo JS |title=Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. |journal=J. Pharmacol. Exp. Ther. |volume=270 |issue= 3 |pages= 1313–8 |year= 1994 |pmid= 7932184 |doi=  }}
*{{cite journal | author=Carter AD, Felber BK, Walling MJ, ''et al.'' |title=Duplicated heavy metal control sequences of the mouse metallothionein-I gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 23 |pages= 7392-6 |year= 1985 |pmid= 6095291 |doi=  }}
*{{cite journal   |vauthors=Pauwels M, van Weyenbergh J, Soumillion A, etal |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105–10 |year= 1994 |pmid= 8119276 |doi=10.1111/j.1432-1033.1994.tb18603.x }}
*{{cite journal  | author=Kondo Y, Kuo SM, Lazo JS |title=Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. |journal=J. Pharmacol. Exp. Ther. |volume=270 |issue= 3 |pages= 1313-8 |year= 1994 |pmid= 7932184 |doi=  }}
*{{cite journal  |vauthors=Vandeghinste N, Proost P, De Ley M |title=Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=46 |issue= 2 |pages= 419–33 |year= 2000 |pmid= 10774930 |doi=  }}
*{{cite journal | author=Pauwels M, van Weyenbergh J, Soumillion A, ''et al.'' |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105-10 |year= 1994 |pmid= 8119276 |doi=  }}
*{{cite journal   |vauthors=Nguyen A, Jing Z, Mahoney PS, etal |title=In vivo gene expression profile analysis of metallothionein in renal cell carcinoma. |journal=Cancer Lett. |volume=160 |issue= 2 |pages= 133–40 |year= 2000 |pmid= 11053642 |doi=10.1016/S0304-3835(00)00534-6 }}
*{{cite journal  | author=Vandeghinste N, Proost P, De Ley M |title=Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=46 |issue= 2 |pages= 419-33 |year= 2000 |pmid= 10774930 |doi=  }}
*{{cite journal  |vauthors=Oppermann B, Zhang W, Magabo K, Kantorow M |title=Identification and spatial analysis of metallothioneins expressed by the adult human lens. |journal=Invest. Ophthalmol. Vis. Sci. |volume=42 |issue= 1 |pages= 188–93 |year= 2001 |pmid= 11133866 |doi= | pmc=2957813 }}
*{{cite journal | author=Nguyen A, Jing Z, Mahoney PS, ''et al.'' |title=In vivo gene expression profile analysis of metallothionein in renal cell carcinoma. |journal=Cancer Lett. |volume=160 |issue= 2 |pages= 133-40 |year= 2000 |pmid= 11053642 |doi=  }}
*{{cite journal   |vauthors=Garrett SH, Belcastro M, Sens MA, etal |title=Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells |journal=J. Toxicol. Environ. Health Part A |volume=64 |issue= 4 |pages= 343–55 |year= 2001 |pmid= 11693492 |doi=10.1080/152873901316981321 }}
*{{cite journal  | author=Oppermann B, Zhang W, Magabo K, Kantorow M |title=Identification and spatial analysis of metallothioneins expressed by the adult human lens. |journal=Invest. Ophthalmol. Vis. Sci. |volume=42 |issue= 1 |pages= 188-93 |year= 2001 |pmid= 11133866 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Garrett SH, Belcastro M, Sens MA, ''et al.'' |title=Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells. |journal=J. Toxicol. Environ. Health Part A |volume=64 |issue= 4 |pages= 343-55 |year= 2001 |pmid= 11693492 |doi=  }}
*{{cite journal   |vauthors=Izmailova E, Bertley FM, Huang Q, etal |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Hawse JR, Cumming JR, Oppermann B, etal |title=Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 2 |pages= 672–9 |year= 2003 |pmid= 12556398 |doi=10.1167/iovs.02-0018  | pmc=2825746 }}
*{{cite journal | author=Izmailova E, Bertley FM, Huang Q, ''et al.'' |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191-7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
*{{cite journal   |vauthors=Sens D, Rossi M, Park S, etal |title=Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2 |journal=J. Toxicol. Environ. Health Part A |volume=66 |issue= 21 |pages= 2031–46 |year= 2003 |pmid= 14555400 |doi=10.1080/713853980 }}
*{{cite journal | author=Hawse JR, Cumming JR, Oppermann B, ''et al.'' |title=Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses. |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 2 |pages= 672-9 |year= 2003 |pmid= 12556398 |doi=  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Sens D, Rossi M, Park S, ''et al.'' |title=Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2. |journal=J. Toxicol. Environ. Health Part A |volume=66 |issue= 21 |pages= 2031-46 |year= 2003 |pmid= 14555400 |doi=  }}
*{{cite journal   |vauthors=Sun NN, Fastje CD, Wong SS, etal |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line |journal=Toxicology and industrial health |volume=19 |issue= 7–10 |pages= 157–63 |year= 2005 |pmid= 15747776 |doi=10.1191/0748233703th185oa }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Lederer CW, Torrisi A, Pantelidou M, etal |title=Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis |journal=BMC Genomics |volume=8|pages= 26 |year= 2007 |pmid= 17244347 |doi= 10.1186/1471-2164-8-26 | pmc=1796866 }}
*{{cite journal | author=Sun NN, Fastje CD, Wong SS, ''et al.'' |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line. |journal=Toxicology and industrial health |volume=19 |issue= 7-10 |pages= 157-63 |year= 2005 |pmid= 15747776 |doi=  }}
*{{cite journal | author=Lederer CW, Torrisi A, Pantelidou M, ''et al.'' |title=Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. |journal=BMC Genomics |volume=8 |issue=  |pages= 26 |year= 2007 |pmid= 17244347 |doi= 10.1186/1471-2164-8-26 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=4493}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


{{protein-stub}}
{{gene-16-stub}}
{{WikiDoc Sources}}

Latest revision as of 06:59, 4 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Metallothionein-1E is a protein that in humans is encoded by the MT1E gene.[1][2][3]


References

  1. ↑ Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.
  2. ↑ Schmidt CJ, Jubier MF, Hamer DH (Jul 1985). "Structure and expression of two human metallothionein-I isoform genes and a related pseudogene". J Biol Chem. 260 (12): 7731–7. PMID 2581970.
  3. ↑ "Entrez Gene: MT1E metallothionein 1E".

Further reading



Retrieved from "https://www.wikidoc.org/index.php?title=MT1E&oldid=1417625"