MT-RNR2
Jump to navigation
Jump to search
| mitochondrially encoded 16S RNA | |
|---|---|
| Identifiers | |
| Symbol | MT-RNR2 |
| Alt. symbols | MTRNR2 |
| Entrez | 4550 |
| HUGO | 7471 |
| UniProt | Q8IVG9 |
| Other data | |
| Locus | Chr. MT [1] |
Mitochondrially encoded 16S RNA (often abbreviated as 16S) is a mitochondrial ribosomal RNA (rRNA)[1][2] that in humans is encoded by the MT-RNR2 gene. The MT-RNR2 gene also encodes the Humanin polypeptide that has been the target of Alzheimer's disease research.[3][4]
The 16S rRNA is the mitochondrial homologue of the prokaryotic 23S and eukaryotic nuclear 28S ribosomal RNAs.[5]
See also
References
- ↑ Noda R, Kim CG, Takenaka O, et al. (2001). "Mitochondrial 16S rRNA sequence diversity of hominoids". J. Hered. 92 (6): 490–6. doi:10.1093/jhered/92.6.490. PMID 11948216.
- ↑ Nagy A, Wilhelm M, Kovacs G (February 2003). "Mutations of mtDNA in renal cell tumours arising in end-stage renal disease". J. Pathol. 199 (2): 237–42. doi:10.1002/path.1273. PMID 12533837.
- ↑ Maximov V, Martynenko A, Hunsmann G, Tarantul V (December 2002). "Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy". Med. Hypotheses. 59 (6): 670–3. doi:10.1016/S0306-9877(02)00223-2. PMID 12445508.
- ↑ Tajima H, Niikura T, Hashimoto Y, et al. (May 2002). "Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults". Neurosci. Lett. 324 (3): 227–31. doi:10.1016/S0304-3940(02)00199-4. PMID 12009529. Archived from the original on 2013-01-22.
- ↑ Eperon, I. C.; Anderson, S.; Nierlich, D. P. (1980-07-31). "Distinctive sequence of human mitochondrial ribosomal RNA genes". Nature. 286 (5772): 460–467. doi:10.1038/286460a0.
| Stub icon | This genetics article is a stub. You can help Wikipedia by expanding it. |
