MGEA5

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Meningioma expressed antigen 5 (hyaluronidase)
Identifiers
Symbols MGEA5 ; FLJ11229; FLJ23355; KIAA0679; MEA5; NCOAT
External IDs Template:OMIM5 Template:MGI HomoloGene8154
RNA expression pattern
File:PBB GE MGEA5 200899 s at tn.png
File:PBB GE MGEA5 200898 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Meningioma expressed antigen 5 (hyaluronidase), also known as MGEA5, is a human gene.[1]


References

  1. "Entrez Gene: MGEA5 meningioma expressed antigen 5 (hyaluronidase)".

Further reading

  • Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. PMID 12168954.
  • Ishikawa K, Nagase T, Suyama M; et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. PMID 9734811.
  • Heckel D, Comtesse N, Brass N; et al. (1998). "Novel immunogenic antigen homologous to hyaluronidase in meningioma". Hum. Mol. Genet. 7 (12): 1859–72. PMID 9811929.
  • Gao Y, Wells L, Comer FI; et al. (2001). "Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain". J. Biol. Chem. 276 (13): 9838–45. doi:10.1074/jbc.M010420200. PMID 11148210.
  • Comtesse N, Maldener E, Meese E (2001). "Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase". Biochem. Biophys. Res. Commun. 283 (3): 634–40. doi:10.1006/bbrc.2001.4815. PMID 11341771.
  • Wells L, Gao Y, Mahoney JA; et al. (2002). "Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase". J. Biol. Chem. 277 (3): 1755–61. PMID 11788610.
  • Farook VS, Bogardus C, Prochazka M (2003). "Analysis of MGEA5 on 10q24.1-q24.3 encoding the beta-O-linked N-acetylglucosaminidase as a candidate gene for type 2 diabetes mellitus in Pima Indians". Mol. Genet. Metab. 77 (1–2): 189–93. PMID 12359146.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
  • Ballif BA, Villén J, Beausoleil SA; et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Toleman C, Paterson AJ, Whisenhunt TR, Kudlow JE (2005). "Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities". J. Biol. Chem. 279 (51): 53665–73. doi:10.1074/jbc.M410406200. PMID 15485860.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Toleman CA, Paterson AJ, Kudlow JE (2006). "The histone acetyltransferase NCOAT contains a zinc finger-like motif involved in substrate recognition". J. Biol. Chem. 281 (7): 3918–25. doi:10.1074/jbc.M510485200. PMID 16356930.
  • Whisenhunt TR, Yang X, Bowe DB; et al. (2006). "Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development". Glycobiology. 16 (6): 551–63. doi:10.1093/glycob/cwj096. PMID 16505006.
  • Toleman C, Paterson AJ, Kudlow JE (2006). "Location and characterization of the O-GlcNAcase active site". Biochim. Biophys. Acta. 1760 (5): 829–39. doi:10.1016/j.bbagen.2006.01.017. PMID 16517082.
  • Cameron EA, Martinez-Marignac VL, Chan A; et al. (2007). "MGEA5-14 polymorphism and type 2 diabetes in Mexico City". Am. J. Hum. Biol. 19 (4): 593–6. doi:10.1002/ajhb.20639. PMID 17546623.

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