ME2 (gene)

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Identifiers
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External IDsGeneCards: [1]
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SpeciesHumanMouse
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NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene.[1][2]

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene.[2]

See also

References

  1. Loeber G, Infante AA, Maurer-Fogy I, Krystek E, Dworkin MB (Mar 1991). "Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli". J Biol Chem. 266 (5): 3016–21. PMID 1993674.
  2. 2.0 2.1 "Entrez Gene: ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial".

Further reading