Lung agenesis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Lung agenesis is defined as partial or complete failure of the lung to form with absence of the parenchyma, the bronchus and the vessels.

Classification

The condition can be unilateral (compatible with life) or bilateral (fatal).

Epidemiology and Demographics

Lung agenesis is extremely rare.

Natural History, Complications, Prognosis

The natural history is variable. Although 50% of patients may die before the age of 5, the remainder of the individuals may be asymptomatic throughout their lives. Bilateral lung agenesis is a lethal anomaly.