Lipoma natural history, complications and prognosis: Difference between revisions

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==Overview==
==Overview==
Common complications of lipoma include [[bleeding]], [[ulceration]], malignant transformation, and recurrence. Prognosis is generally excellent.  
Common complications of lipoma include [[bleeding]], [[ulceration]], malignant transformation, and recurrence. Prognosis is generally excellent.  


==Natural History==
==Natural History==

Revision as of 20:23, 21 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Common complications of lipoma include bleeding, ulceration, malignant transformation, and recurrence. Prognosis is generally excellent.

Natural History

Complications

The complications of lipoma listed below:

Prognosis

  • Lipomas are rarely life-threatening and the common subcutaneous lipomas are not a serious condition. Lipomas growing in internal organs can be more dangerous. [1][2]
  • Malignant transformation of lipomas into liposarcomas is very rare and most liposarcomas are not produced from pre-existing benign lesions. A few cases of malignant transformation have been described for bone and kidney lipomas,[3][4] but it is possible these few reported cases were well-differentiated liposarcomas in which the subtle malignant characteristics were missed when the tumour was first examined.[5]
  • Deep lipomas have a greater tendency to recur than superficial lipomas, because complete surgical removal of deep lipomas is not always possible.[6]

References

  1. Thompson WM (1 April 2005). "Imaging and findings of lipomas of the gastrointestinal tract". AJR Am J Roentgenol. 184 (4): 1163–71. doi:10.2214/ajr.184.4.01841163. PMID 15788588.
  2. Taylor AJ, Stewart ET, Dodds WJ (1 December 1990). "Gastrointestinal lipomas: a radiologic and pathologic review". AJR Am J Roentgenol. 155 (6): 1205–10. doi:10.2214/ajr.155.6.2122666. PMID 2122666.
  3. Milgram JW (1990). "Malignant transformation in bone lipomas". Skeletal Radiol. 19 (5): 347–52. doi:10.1007/BF00193088. PMID 2165632.
  4. Lowe BA, Brewer J, Houghton DC, Jacobson E, Pitre T (May 1992). "Malignant transformation of angiomyolipoma". J. Urol. 147 (5): 1356–8. PMID 1569683.
  5. Goldblum, John R.; Weiss, Sharon W.; Enzinger, Franz M. (2008). Enzinger and Weiss's soft tissue tumors (5th ed.). Mosby Elsevier. ISBN 0-323-04628-2.
  6. Fletcher, C.D.M., Unni, K.K., Mertens, F. (2002). Pathology and Genetics of Tumours of Soft Tissue and Bone. World Health Organization Classification of Tumours. 4. Lyon: IARC Press. ISBN 92-832-2413-2.


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