Linitis plastica other diagnostic studies: Difference between revisions
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{{Linitis plastica}} | {{Linitis plastica}} | ||
{{CMG}}{{AE}} {{STM}} | |||
==Overview== | |||
On upper GI [[endoscopy]], linitis plastica may show superficial [[ulcers]] and/or [[inflammation]]. On [[endoscopic ultrasound]], abnormal thickening of the stomach wall is a characteristic finding.<ref name=oo>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273 Accessed on December 9, 2015.</ref> | |||
==Upper GI Endoscopy== | |||
*[[Esophagogastroduodenoscopy]] ([[EGD]]) or upper GI endoscopy with multiple deep tissue biopsies is performed to confirm the diagnosis of linitis plastica.<ref name="pmid25435971">{{cite journal| author=Maeda E, Oryu M, Tani J, Miyoshi H, Morishita A, Yoneyama H et al.| title=Characteristic waffle-like appearance of gastric linitis plastica: A case report. | journal=Oncol Lett | year= 2015 | volume= 9 | issue= 1 | pages= 262-264 | pmid=25435971 | doi=10.3892/ol.2014.2688 | pmc=PMC4246919 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25435971 }} </ref> | |||
**[[Mucosa]] is usually spared. It may look innocent or show superficial ulcers with inflammatory changes as seen in [[gastritis]], thus masking the [[malignant]] nature of linitis plastica. The disease being potentially in the [[submucosa]] and muscularis propria layers, mucosal biopsies are falsely negative. | |||
**[[Endoscopic ultrasound]] guided [[fine needle aspiration]] aids in the diagnosis of linitis plastica.<ref name="pmid20214236">{{cite journal| author=Mastoraki A, Papanikolaou IS, Sakorafas G, Safioleas M| title=Facing the challenge of managing linitis plastica--review of the literature. | journal=Hepatogastroenterology | year= 2009 | volume= 56 | issue= 96 | pages= 1773-8 | pmid=20214236 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20214236 }} </ref> | |||
*Endoscopic ultrasound may be also performed to understand the depth of tumor invasion as well as spread of the disease to the adjacent structures. | |||
**A 10-20mm thickening of the [[submucosa]]l layer is usually present.<ref name=oo>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273 Accessed on December 9, 2015.</ref> | |||
==References== | ==References== | ||
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Revision as of 13:46, 20 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
On upper GI endoscopy, linitis plastica may show superficial ulcers and/or inflammation. On endoscopic ultrasound, abnormal thickening of the stomach wall is a characteristic finding.[1]
Upper GI Endoscopy
- Esophagogastroduodenoscopy (EGD) or upper GI endoscopy with multiple deep tissue biopsies is performed to confirm the diagnosis of linitis plastica.[2]
- Mucosa is usually spared. It may look innocent or show superficial ulcers with inflammatory changes as seen in gastritis, thus masking the malignant nature of linitis plastica. The disease being potentially in the submucosa and muscularis propria layers, mucosal biopsies are falsely negative.
- Endoscopic ultrasound guided fine needle aspiration aids in the diagnosis of linitis plastica.[3]
- Endoscopic ultrasound may be also performed to understand the depth of tumor invasion as well as spread of the disease to the adjacent structures.
- A 10-20mm thickening of the submucosal layer is usually present.[1]
References
- ↑ 1.0 1.1 Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273 Accessed on December 9, 2015.
- ↑ Maeda E, Oryu M, Tani J, Miyoshi H, Morishita A, Yoneyama H; et al. (2015). "Characteristic waffle-like appearance of gastric linitis plastica: A case report". Oncol Lett. 9 (1): 262–264. doi:10.3892/ol.2014.2688. PMC 4246919. PMID 25435971.
- ↑ Mastoraki A, Papanikolaou IS, Sakorafas G, Safioleas M (2009). "Facing the challenge of managing linitis plastica--review of the literature". Hepatogastroenterology. 56 (96): 1773–8. PMID 20214236.