Linear IgA bullous dermatosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.^[1]^:135 It was first described by Tadeusz Chorzelski in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:^[2]^:587

Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. ^[1]
Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. ^[1]

Diagnosis

Physical Examination

Skin

Trunk And Extremities

Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]
Childhood linear IgA disease. Adapted from Dermatology Atlas.^[3]

References

↑ ^1.0 ^1.1 ^1.2 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 "Dermatology Atlas".

Template:Cutaneous-condition-stub Template:Vesiculobullous disease

[Andrews-1] 1.0 ^1.1 ^1.2 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

[Fitz2-2] Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

[Dermatology_Atlas-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 ^3.18 ^3.19 ^3.20 "Dermatology Atlas".

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