Levine's sign

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Levine's sign is a clenched fist held over the chest to describe ischemic chest pain. It is named for Dr. Sam Levine who first observed that many patients suffering from chest pain made this same sign to describe their symptoms.

It is seen in patients with MI (myocardial infarction) in the emergency setting, and those with angina pectoris in routine clinics.


  • Edmondstone WM.Cardiac chest pain: does body language help the diagnosis? BMJ 1995;311:1660-1. PMID 8541748.