Latanoprost detailed information

Latanoprost detailed information

Clinical data
Routes of administration	Topical (eye drops)
ATC code	S01EE01 (WHO)
Pharmacokinetic data
Elimination half-life	17 minutes
Identifiers
IUPAC name propan-2-yl 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pentyl) -cyclopentyl] hept-5-enoate
CAS Number	130209-82-4
PubChem CID	60798
DrugBank	APRD01065
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C26H40O5
Molar mass	432.593 g/mol

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Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.

It is also known by the brand name of Xalatan manufactured by Pfizer.

Side effects

Possible side effects:

• May cause reddening of the eyes (hyperemia)
• May cause blurred vision;
• May cause eyelid redness;
• May permanently darken eyelashes;
• May cause eye discomfort;
• May eventually cause permanent darkening of the iris to brown (heterochromia);
• May cause a temporary burning sensation during use.
• May cause thickening of the eyelashes.
• Rarely, herpes simplex keratitis.

External links

• Xalatan (manufacturer's website)
• Hara T (2001). "Increased iris pigmentation after use of latanoprost in Japanese brown eyes". Nippon Ganka Gakkai Zasshi. 105 (5): 314–21. PMID 11406947.

Template:Antiglaucoma preparations and miotics Template:Prostaglandins