Kawasaki disease history and symptoms: Difference between revisions

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{{CMG}}; {{AE}} {{SH}}
{{CMG}}; {{AE}} {{SH}}
== Overview ==
== Overview ==
Kawasaki disease often begins with a high and persistent [[fever]] that is not very responsive to normal doses of [[acetaminophen]] or [[ibuprofen]]. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop red eyes, [[Mucous membrane|mucous membranes]], and lips, a "[[strawberry tongue]]", iritis, keratic precipitates (detectable by an ophthalmologist but usually too small to be seen by the naked eye), and swollen [[Lymph node|lymph nodes]]. [[Skin rash|Skin rashes]] occur early in the disease, and peeling of the skin in the [[genital area]], hands, and feet may occur in later phases. Some of these symptoms may come and go during the course of the illness.  
Kawasaki disease often begins with a high and persistent [[fever]] that is not very responsive to normal doses of [[acetaminophen]] or [[ibuprofen]]. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop redness of the eyes, [[Mucous membrane|mucous membranes]], and lips, a "[[strawberry tongue]]", [[iritis]], keratic precipitates (detected by an [[Ophthalmology|ophthalmologist]] but usually too small to be seen by the naked eye), and swollen [[Lymph node|lymph nodes]]. [[Skin rash]] occur early in the [[disease]], and peeling of the [[skin]] in the [[genital area]], [[Hand|hands]], and feet may occur in the later phases. Some of these [[Symptom|symptoms]] may come and go during the course of the [[illness]].  


==History and Symptoms==
==History and Symptoms==
Symptoms of Kawasaki disease include a high and persistent [[fever]], skin rashes, [[desquamation]] of skin, [[irritability]], erythematous eyes, lips and [[Mucous membrane|mucous membranes]], [[strawberry tongue]], [[iritis]], keratic precipitates, and swollen [[Lymph node|lymph nodes]].<ref name="McCrindleRowley2017">{{cite journal|last1=McCrindle|first1=Brian W.|last2=Rowley|first2=Anne H.|last3=Newburger|first3=Jane W.|last4=Burns|first4=Jane C.|last5=Bolger|first5=Anne F.|last6=Gewitz|first6=Michael|last7=Baker|first7=Annette L.|last8=Jackson|first8=Mary Anne|last9=Takahashi|first9=Masato|last10=Shah|first10=Pinak B.|last11=Kobayashi|first11=Tohru|last12=Wu|first12=Mei-Hwan|last13=Saji|first13=Tsutomu T.|last14=Pahl|first14=Elfriede|title=Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association|journal=Circulation|volume=135|issue=17|year=2017|pages=e927–e999|issn=0009-7322|doi=10.1161/CIR.0000000000000484}}</ref>
[[Symptom|Symptoms]] of Kawasaki disease include a high and persistent [[fever]], skin rashes, [[desquamation]] of skin, [[irritability]], [[erythema]] of the [[Eye|eyes]], [[Lip|lips]], and [[Mucous membrane|mucous membranes]], [[strawberry tongue]], [[iritis]], keratic precipitates, and swollen [[Lymph node|lymph nodes]].<ref name="McCrindleRowley2017">{{cite journal|last1=McCrindle|first1=Brian W.|last2=Rowley|first2=Anne H.|last3=Newburger|first3=Jane W.|last4=Burns|first4=Jane C.|last5=Bolger|first5=Anne F.|last6=Gewitz|first6=Michael|last7=Baker|first7=Annette L.|last8=Jackson|first8=Mary Anne|last9=Takahashi|first9=Masato|last10=Shah|first10=Pinak B.|last11=Kobayashi|first11=Tohru|last12=Wu|first12=Mei-Hwan|last13=Saji|first13=Tsutomu T.|last14=Pahl|first14=Elfriede|title=Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association|journal=Circulation|volume=135|issue=17|year=2017|pages=e927–e999|issn=0009-7322|doi=10.1161/CIR.0000000000000484}}</ref>
===History===
===History===
Patients with Kawasaki disease may have a positive history of:
[[Patient|Patients]] with Kawasaki disease may have a positive history of:
*[[Fever]] not responsive to [[acetaminophen]] or [[ibuprofen]]
*[[Fever]] not responsive to [[acetaminophen]] or [[ibuprofen]]
===Common Symptoms===
===Common Symptoms===
{| align="right"
{| align="right"
|[[Image:Kawasaki symptoms B.jpg|thumb|center|500px|Source:commons.wikimedia. org, demonstrates a "strawberry tongue" caused by prominence of the tongue papillae by Kawasaki_symptoms.jpg: Dong Soo Kimderivative work: Natr (talk) - Kawasaki_symptoms.jpg, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=12776137]]
|[[File:Kawasaki tongue.jpg|300px|thumb|center| Strawberry tongue and bright red, swollen lips with vertical cracking and bleeding.<ref>By Kawasaki_symptoms.jpg: Dong Soo Kimderivative work: Natr (talk) - Kawasaki_symptoms.jpg, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=12776137</ref>]]
|}
|}
Common symptoms of Kawasaki disease include:
Common [[Symptom|symptoms]] of Kawasaki disease include:
*High grade [[fever]]
*High grade [[fever]]
**Greater than 39&nbsp;°C or 102&nbsp;°F; often as high as 40&nbsp;°C  or 104&nbsp;°F that normally lasts for more than a week if left untreated
**Greater than 39&nbsp;°C or 102&nbsp;°F; often as high as 40&nbsp;°C  or 104&nbsp;°F that normally lasts for more than a week if left untreated
*[[Red eye|Conjunctival injection]]
*[[Red eye|Redness of eyes]]
*Fissuring of the lips
*Fissuring of the lips
*[[Strawberry tongue]] with prominent papillae
*[[Strawberry tongue|Red discoloration of the tongue]]
*Erythematous palms of the hand and soles of the feet
*[[Erythema|Redness]] of [[Hand|palms]] and [[Sole (foot)|soles]]
*[[Desquamation]] of skin
*[[Desquamation|Peeling of skin]]
*Erythematous mucous membranes
*Red [[Mucous membrane|mucous membranes]]
*Cervical [[lymphadenopathy]]
*[[lymphadenopathy|Neck swelling]]
*[[Rash]] over the trunk
*[[Rash]]
 
===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of Kawasaki disease include:
Less common [[Symptom|symptoms]] of Kawasaki disease include:
*[[Uveitis]]
*[[Uveitis|Eye redness, pain, and blurred vision]]
*[[Tachycardia]]
*[[Tachycardia]]
*[[Nausea and vomiting|Vomiting]]
*[[Nausea and vomiting|Vomiting]]

Latest revision as of 19:48, 14 February 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

Kawasaki disease often begins with a high and persistent fever that is not very responsive to normal doses of acetaminophen or ibuprofen. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop redness of the eyes, mucous membranes, and lips, a "strawberry tongue", iritis, keratic precipitates (detected by an ophthalmologist but usually too small to be seen by the naked eye), and swollen lymph nodesSkin rash occur early in the disease, and peeling of the skin in the genital area, hands, and feet may occur in the later phases. Some of these symptoms may come and go during the course of the illness.

History and Symptoms

Symptoms of Kawasaki disease include a high and persistent fever, skin rashes, desquamation of skin, irritability, erythema of the eyes, lips, and mucous membranes, strawberry tongue, iritis, keratic precipitates, and swollen lymph nodes.[1]

History

Patients with Kawasaki disease may have a positive history of:

Common Symptoms

Strawberry tongue and bright red, swollen lips with vertical cracking and bleeding.[2]

Common symptoms of Kawasaki disease include:

Less Common Symptoms

Less common symptoms of Kawasaki disease include:

References

  1. McCrindle, Brian W.; Rowley, Anne H.; Newburger, Jane W.; Burns, Jane C.; Bolger, Anne F.; Gewitz, Michael; Baker, Annette L.; Jackson, Mary Anne; Takahashi, Masato; Shah, Pinak B.; Kobayashi, Tohru; Wu, Mei-Hwan; Saji, Tsutomu T.; Pahl, Elfriede (2017). "Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association". Circulation. 135 (17): e927–e999. doi:10.1161/CIR.0000000000000484. ISSN 0009-7322.
  2. By Kawasaki_symptoms.jpg: Dong Soo Kimderivative work: Natr (talk) - Kawasaki_symptoms.jpg, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=12776137

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