KLF10

Kruppel-like factor 10
Identifiers
Symbols	KLF10 ; EGRA; TIEG; TIEG1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4135
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE KLF10 202393 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Kruppel-like factor 10, also known as KLF10, is a human gene.

See also

• Kruppel-like factors

Further reading

• Subramaniam M, Harris SA, Oursler MJ; et al. (1996). "Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts". Nucleic Acids Res. 23 (23): 4907–12. PMID 8532536.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Blok LJ, Grossmann ME, Perry JE, Tindall DJ (1996). "Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation". Mol. Endocrinol. 9 (11): 1610–20. PMID 8584037.CS1 maint: Multiple names: authors list (link)
• Tachibana I, Imoto M, Adjei PN; et al. (1997). "Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells". J. Clin. Invest. 99 (10): 2365–74. PMID 9153278.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Subramaniam M, Hefferan TE, Tau K; et al. (1998). "Tissue, cell type, and breast cancer stage-specific expression of a TGF-beta inducible early transcription factor gene". J. Cell. Biochem. 68 (2): 226–36. PMID 9443078.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fautsch MP, Vrabel A, Subramaniam M; et al. (1998). "TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters". Genomics. 51 (3): 408–16. doi:10.1006/geno.1998.5388. PMID 9721211.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cook T, Gebelein B, Mesa K; et al. (1998). "Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth". J. Biol. Chem. 273 (40): 25929–36. PMID 9748269.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hefferan TE, Reinholz GG, Rickard DJ; et al. (2000). "Overexpression of a nuclear protein, TIEG, mimics transforming growth factor-beta action in human osteoblast cells". J. Biol. Chem. 275 (27): 20255–9. doi:10.1074/jbc.C000135200. PMID 10816551.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gunther M, Laithier M, Brison O (2000). "A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening". Mol. Cell. Biochem. 210 (1–2): 131–42. PMID 10976766.CS1 maint: Multiple names: authors list (link)
• Antonello D, Moore PS, Zamboni G; et al. (2002). "Absence of mutations in the transforming growth factor-beta inducible early gene 1, TIEG1, in pancreatic cancer". Cancer Lett. 183 (2): 179–83. PMID 12065093.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johnsen SA, Subramaniam M, Monroe DG; et al. (2002). "Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue". J. Biol. Chem. 277 (34): 30754–9. doi:10.1074/jbc.M204812200. PMID 12072443.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johnsen SA, Subramaniam M, Janknecht R, Spelsberg TC (2002). "TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses". Oncogene. 21 (37): 5783–90. doi:10.1038/sj.onc.1205681. PMID 12173049.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chrisman HR, Tindall DJ (2003). "Identification and characterization of a consensus DNA binding element for the zinc finger transcription factor TIEG/EGRalpha". DNA Cell Biol. 22 (3): 187–99. doi:10.1089/104454903321655819. PMID 12804117.
• Noti JD, Johnson AK, Dillon JD (2004). "The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter". J. Biol. Chem. 279 (26): 26948–58. doi:10.1074/jbc.M310634200. PMID 15087465.CS1 maint: Multiple names: authors list (link)
• Reinholz MM, An MW, Johnsen SA; et al. (2004). "Differential gene expression of TGF beta inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue". Breast Cancer Res. Treat. 86 (1): 75–88. doi:10.1023/B:BREA.0000032926.74216.7d. PMID 15218362.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johnsen SA, Subramaniam M, Effenberger KE, and Spelsberg TC (2004). "The TGFβ Inducible Early Gene Plays a Central Role in the Anti-Proliferative Response to TGFβ". Signal Transduction. 4: 29–35. doi:10.1002/sita.200400032.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Subramaniam M, Gorny G, Johnsen SA, Monroe DG, Evans GL, Fraser DG, Rickard DJ, Rasmussen K, van Deursen JMA, Turner RT, Oursler MJ, and Spelsberg TC (2005). "TIEG1 Null Mouse-Derived Osteoblasts Are Defective in Mineralization and in Support of Osteoclast Differentiation In Vitro". Mol. Cell. Biol. 25: 1191–1199. doi:10.1128/MCB.25.3.1191-1199.2005. PMID 15657444.CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fueki N, Sagara H, Akimoto K; et al. (2007). "Interleukin-10 regulates transforming growth factor-beta signaling in cultured human bronchial epithelial cells". Respiration; international review of thoracic diseases. 74 (4): 454–9. doi:10.1159/000101057. PMID 17377371.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jin W, Di G, Li J; et al. (2007). "TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade". FEBS Lett. 581 (20): 3826–32. doi:10.1016/j.febslet.2007.07.008. PMID 17659279.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Subramaniam M, Hawse JR, Johnsen SA, and Spelsberg TC (2007). "TIEG1: An Important Regulator of Multiple Biological Processes and Disease States". J. Cell. Biochem. 102 (3): 539–548. doi:10.1002/jcb.21492. PMID 17729309.CS1 maint: Multiple names: authors list (link)

External links

• KLF10+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.