The differential diagnosis for jaundice, pruritis and RUQ pain are:
| Classification of jaundice based on etiology
|
Disease
|
History and clinical manifestations
|
Diagnosis
|
| Lab Findings
|
Other blood tests
|
Other diagnostic
|
| Family history
|
Fever
|
RUQ Pain
|
Pruritis
|
AST
|
ALT
|
ALK
|
BLR Indirect
|
BLR Direct
|
Viral serology
|
| Jaundice
|
Cholestatic Jaundice
|
Common bile duct stone
|
-/+
|
-
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
-
|
Dilated ducts on ultrasond
|
CT/ERCP
|
| Hepatitis A cholestatic type
|
-
|
-/+
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
+
|
HAV- AB
|
Abdominal ultrasound
|
| EBV / CMV hepatitis
|
-
|
-/+
|
+
|
+
|
N
|
N
|
↑
|
N
|
↑
|
+
|
Positive serology
|
|
| Primary biliary cirrhosis
|
-/+
|
-
|
-/+
|
+
|
N/↑
|
N/↑
|
↑
|
N
|
↑
|
-
|
AMA positive
|
Liver biopsy
|
| Primary sclerosing cholangitis
|
-/+
|
-
|
-/+
|
+
|
N/↑
|
N/↑
|
↑
|
N
|
↑
|
-
|
Beading on MRCP
|
Liver biopsy
|
|