Isopropyl alcohol: Difference between revisions

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{{Chembox new
{{DrugProjectFormSinglePage
|   Name = Isopropyl alcohol
|authorTag={{Ammu}}
|   ImageFile = Isopropanol-skeletal.png  
|OTC=Yes
|   ImageSize = 150px
|genericName=Topical antimicrobial
|   ImageName = Isopropyl alcohol  
|aOrAn=an
|   ImageFile1 = Isopropanol-3D-vdW.png
|drugClass=[[antiseptic]]
|   ImageSize1 = 150px
|indicationType=treatment
|   ImageName1 = Isopropanol
|indication=cuts, scrapes and minor [[muscular aches]]
|   IUPACName = Propan-2-ol  
|adverseReactions=[[hypersensitivity]]
|  OtherNames = 2-propanol, isopropanol,<br/>Isopropyl alcohol  
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
 
* Content
 
<!--Adult Indications and Dosage-->
 
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=to decrease germs in minor cuts and scrapes.
helps relieve minor muscular aches due to exertion.
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
 
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
 
<!--Pediatric Indications and Dosage-->
 
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed=There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Off-Label Use and Dosage (Pediatric)-->
 
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport=There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
 
<!--Contraindications-->
|warnings=* For external use only
* Flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally
* Ask a doctor before use if you have deep puncture wounds or serious burns
* When using this product do not get into eyes or mucous membranes use only in a well-ventilated area.
* Stop use and ask a doctor if condition persists or gets worse.
* Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|drugInteractions=<!--Use in Specific Populations-->
|useInPregnancyFDA=* '''Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
 
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
 
<!--Administration and Monitoring-->
|administration=* [[Topical]]
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
 
<!--Overdosage-->
|drugBox={{chembox2
| Watchedfields = changed
| verifiedrevid = 477002700
|  Name = Isopropyl alcohol
| ImageFileL1 = Isopropyl alcohol.png
| ImageNameL1 = Skeletal formula of isopropyl alcohol
| ImageFileR1 = Isopropyl alcohol.png
| ImageNameR1 = Ball-and-stick model of isopropyl alcohol
| PIN = 2-Propanol
| IUPACName =isopropyl alcohol
| OtherNames = Propan-2-ol; Isopropanol; [[Rubbing alcohol]]; ''sec''-Propyl alcohol; ''s''-Propanol; iPrOH; IPA
| Section1 = {{Chembox Identifiers
| Section1 = {{Chembox Identifiers
|  SMILES = CC(O)C  
|  ChEBI_Ref = {{ebicite|correct|EBI}}
|   CASNo = 67-63-0  
| ChEBI = 17824
|   RTECS = NT8050000  
| SMILES = CC(O)C
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ND2M416302
| UNNumber = 1219
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 582
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = KFZMGEQAYNKOFK-UHFFFAOYSA-N
| CASNo = 67-63-0
| CASNo_Ref = {{cascite|correct|CAS}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 3644
| PubChem = 3776
| RTECS = NT8050000
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00137
| ATCCode_prefix = D08
| ATCCode_suffix = AX05
   }}
   }}
| Section2 = {{Chembox Properties
| Section2 = {{Chembox Properties
|  Formula = C<sub>3</sub>H<sub>8</sub>O  
|  C=3|H=8|O=1
|  MolarMass = 60.10 g/mol
|  Appearance = Colorless liquid
|  Appearance = Colorless liquid  
|  Density = 0.786 g/cm<sup>3</sup> (20 °C)
|  Density = 0.785 g/cm³, liquid 
|  Solubility = [[miscible]]
|  Solubility = Fully [[miscible]]  
|  SolubleOther = miscible in [[benzene]], [[chloroform]], [[ethanol]], [[ether]], [[glycerin]] <br> soluble in [[acetone]] <br> insoluble in [[salt]] solutions
|  MeltingPt = -89 °C (185 K)
|  MeltingPtC = −89
|  BoilingPt = 82.3 °C (355 K)
|  BoilingPtC = 82.6
|  pKa = 16.5 for H on [[hydroxyl]]
|  pKa = 16.5<ref>{{cite journal|author=Reeve, W.; Erikson, C.M.; Aluotto, P.F. |journal=Can. J. Chem.|year=1979|volume=57|issue=20|pages= 2747|doi=10.1139/v79-444|title=A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides}}</ref>
|  Viscosity = 2.86 c[[Poise|P]] at 15 °C<br/>1.77 c[[Poise|P]] at 30 °C  
|  Viscosity = 2.86 c[[Poise|P]] at 15 °C<br>1.96 c[[Poise|P]] at 25 °C<ref name = yaws>{{cite book | title = Chemical Properties Handbook | author = Yaws, C.L. | publisher = [[McGraw-Hill]] | year = 1999 | isbn = 0-07-073401-1}}</ref><br>1.77 c[[Poise|P]] at 30 °C<ref name = yaws/>
|  Dipole = 1.66 [[Debye|D]] (gas)  
|  Dipole = 1.66 [[Debye|D]] (gas)
|  RefractIndex = 1.3776
   }}
   }}
| Section7 = {{Chembox Hazards
| Section7 = {{Chembox Hazards
|  ExternalMSDS = [http://physchem.ox.ac.uk/MSDS/PR/2-propanol.html External MSDS]  
|  EU-classification = Highly flammable (F), Irritating (Xi)
|  MainHazards = Flammable  
|  ExternalMSDS = [http://msds.chem.ox.ac.uk/PR/2-propanol.html External MSDS]
|  FlashPt = 12 °C
|  MainHazards = Flammable
|  RPhrases = {{R11}} {{R36}}  
|  ExploLimits = 2–12.7%
|  RPhrases = {{R11}} {{R36}} {{R67}}
|  SPhrases = {{S7}} {{S16}} {{S24}} {{S25}} {{S26}}
|  SPhrases = {{S7}} {{S16}} {{S24}} {{S25}} {{S26}}
|  GHSPictograms = {{GHS exclamation mark}} {{GHS flame}}
|  GHSSignalWord = '''Danger'''
|  HPhrases = {{H-phrases|225|319|336}}
|  PPhrases = {{P-phrases|210|261|305+351+338}}
|  NFPA-H = 1 <!--http://www.telecheminternational.com/IPA_Reagent_ACS.PDF-->
|  NFPA-F = 3
|  NFPA-R = 0
|  Autoignition = {{convert|399|C|F}}
|  FlashPt = Open cup:  {{convert|11.7|C|F}}<br>Closed cup: {{convert|13|C|F}}
|  TLV-TWA = 980 mg/m<sup>3</sup>
|  TLV-STEL = 1225 mg/m<sup>3</sup>
|  LD50 = 3600 mg/kg (oral, mouse)<br> 12800 mg/kg (dermal, rabbit)<br> [[Median lethal concentration|LC<sub>50</sub>]] = 53000 mg/m<sup>3</sup> (inhalation, mouse)
|  PEL = TWA 400 ppm (980 mg/m<sup>3</sup>)<ref>{{PGCH|0359}}</ref>
   }}
   }}
| Section8 = {{Chembox Related
| Section8 = {{Chembox Related
|  Function = [[alcohol]]s  
|  Function = [[alcohol]]s
|  OtherFunctn = [[1-Propanol|1-propanol]],<br/>[[ethanol]], [[2-Butanol|2-butanol]]}}
|  OtherFunctn = [[1-Propanol]], [[ethanol]], [[2-butanol]]
  }}
}}
}}
{{CMG}}
|mechAction=<!--Structure-->
|structure=<!--Pharmacodynamics-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.


<!--Pharmacokinetics-->
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.


<!--Nonclinical Toxicology-->
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.


'''Isopropyl alcohol''' (also '''isopropanol''', '''iso''', '''[[rubbing alcohol]]''', or the abbreviation '''IPA''') is a common name for '''propan-2-ol''', a colorless, flammable [[chemical compound]] with a strong odor.  It has the [[chemical formula]] C<sub>3</sub>H<sub>8</sub>O and is the simplest example of a [[Alcohol#Primary.2C secondary.2C and tertiary alcohols|''secondary alcohol'']], where the [[alcohol]] carbon is attached to two other carbons.  It is an [[isomer]] of [[Propan-1-ol|propanol]].
<!--Clinical Studies-->
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.


==Manufacture==
<!--How Supplied-->
|packLabel=<!--Patient Counseling Information-->
|fdaPatientInfo=* Apply to skin directly or with clean gauze, cotton or swab.
* For rubbing, apply liberally and rub with hands.
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.


Isopropyl alcohol is produced by combining water and [[propylene]].<ref>{{cite encyclopedia
<!--Brand Names-->
  | title =Isopropyl Alcohol, by John E. Logsdon and Richard A. Loke
|brandNames=*  ISOPROPYL RUBBING ALCOHOL®<ref>{{Cite web | title =ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid   | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ff80a29c-ed8b-4aa2-badf-f8d11172e52d}}</ref>
   | encyclopedia =Kirk‑Othmer Encyclopedia of Chemical Technology
  | publisher =John Wiley & Sons, Inc
  | date =Article Online Posting Date: December 4, 2000
  | accessdate = 2007-08-30 }}</ref> There are two processes for achieving this: indirect hydration (sulfuric acid process) and direct hydration. The former process, which can use low quality propylene,  predominates in the USA while the latter process, which requires high-purity propylene, is more commonly used in Europe. These processes give predominantely isopropyl alcohol rather than propan-1-ol because the addition of water (or sulfuric acid) to propylene follows [[Markovnikov's rule]].


The indirect process reacts proplyene with [[sulfuric acid]] to form a mixture of sulfate esters. Subsequent [[hydrolysis]] of these esters produces isopropyl alcohol. Direct hydration reacts propylene and water, either in gas or liquid phases, at high pressures in the presence of solid or supported acidic [[catalysts]]. Both types of processes require that the isopropyl alcohol be separated from water and other by-products by [[distillation]]. Isopropyl alcohol and water form an [[azeotrope]] and simple distillation gives a material which is 87.9% by weight isopropyl alcohol and 12.1% by weight water.<ref>CRC Handbook of Chemistry and Physics, 44th ed. pp 2143-2184</ref> Pure (anhydrous) isopropyl alcohol is made by [[azeotropic distillation]] of the "wet" isopropyl alcohol using either [[diisopropyl ether]] or [[cyclohexane]] as azeotroping agents.
<!--Look-Alike Drug Names-->
|drugShortage=
}}
{{LabelImage
|fileName=IPL 01.jpg
}}
{{LabelImage
|fileName=DailyMed - ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid .png
}}
<!--Pill Image-->


==Uses==
[[Sterilization (microbiology)|Sterilizing]] pads typically contain a 60-70% [[solution]] of isopropanol in [[water (molecule)|water]]. Isopropyl alcohol is also commonly used as a [[cleaner]] and [[solvent]] in industry.  It is also used as a [[gasoline]] additive for dissolving water or ice in fuel lines. Although Isopropanol is sometimes sold as "Isopropyl Rubbing Alcohol, 70% (or 90%)" and "Isopropyl Rubbing Alcohol, 99%" (harder to find but generally more useful for experimenters & cleaning uses), there is no isopropyl alcohol in the [[United States Pharmacopeia]] formula for [[Rubbing alcohol|Rubbing alcohol, U.S.P.]]. It is used as a [[disinfectant]], and is a common solvent.


Isopropanol is a major ingredient in "dry-gas" [[fuel additive]].  In significant quantities, [[water]] is a problem in fuel tanks as it separates from the gasoline and can freeze in the supply lines at cold temperatures.  The isopropanol does not remove the water from the gasoline.  Rather, the isopropanol solubilizes the water in the gasoline.  Once [[soluble]], the water does not pose the same risk as insoluble water as it will no longer accumulate in the supply lines and freeze.


It is also a very good cleaning agent and often used for cleaning [[electronics|electronic]] devices such as contact pins (like those on [[read-only memory|ROM]] [[cartridge (electronics)|cartridges]]), [[magnetic tape]] deck and [[floppy disk]] drive heads, the lenses of [[lasers]] in [[optical disc]] drives (e.g. [[CD]], [[DVD]]) and removing [[thermal paste]] from [[central processing unit|CPUs]]. It is also used to clean [[liquid crystal display|LCD]] and glass [[computer monitor]] screens (at some risk to the anti-reflection coating of the screen), and used by many music shops to give second-hand or worn [[Gramophone record|records]] newer looking sheens. It cleans white boards very well and other unwanted ink related marks. Isopropyl alcohol also works well at removing smudges, dirt, and fingerprints from [[cell phones]] and [[PDA]]s.
<!--Label Display Image-->


==Chemistry==
Unlike [[ethanol]] or [[methanol]], isopropanol can be separated from aqueous solutions by adding a salt such as [[sodium chloride]], [[sodium sulfate]], or any of several other inorganic salts.<ref>''Merck Index of Chemicals and Drugs'', 9th ed. monograph 5069</ref> The process is colloquially called [[salting out]], and causes concentrated isopropanol to separate into a distinct layer.


Being a secondary alcohol, isopropanol can be [[Redox|oxidised]] to the [[ketone]] [[acetone]].  This can be achieved using oxidising agents such as [[chromic acid]], or by [[dehydrogenation]] of isopropanol over a heated copper [[catalyst]]:


(CH<sub>3</sub>)<sub>2</sub>CH-OH  →  [[Acetone|(CH<sub>3</sub>)<sub>2</sub>C=O]]  +  [[Hydrogen|H<sub>2</sub>]]


Isopropanol may be converted to [[2-bromopropane]] using [[phosphorus tribromide]], or dehydrated to [[propylene]] by heating with [[sulfuric acid]]. 


Isopropanol is often used as a [[hydride]] source in the [[Meerwein-Ponndorf-Verley reduction]].
<!--Category-->


Like most alcohols, isopropyl alcohol reacts with active [[metal]]s such as [[potassium]] to form [[alkoxide]]s which can be called ''isopropoxides''.  The reaction with [[aluminium]] (initiated by a trace of [[Mercury (element)|mercury]]) is used to prepare the catalyst [[aluminium isopropoxide]].
[[Category:Drug]]
 
Isopropanol has a maximal [[absorbance]] at 204 nm in an [[Ultraviolet-visible spectroscopy|ultraviolet-visible]] spectrum.
 
==Safety==
Isopropyl alcohol vapor is heavier than air and is highly [[flammable]] with a very wide combustible range.  It should be kept away from heat and open flame. When mixed with air or other oxidizers it can explode through [[deflagration]].<ref>{{cite web | url=http://physchem.ox.ac.uk/MSDS/PR/2-propanol.html |title=Safety (MSDS) data for 2-propanol |accessdate=2006-09-28}}</ref>
 
Isopropyl alcohol is oxidized by the liver into [[acetone]]. [[Symptom]]s of isopropyl alcohol poisoning include [[flushing (physiology)|flushing]], [[headache]], [[dizziness]], [[CNS depression]], [[nausea]], [[vomiting]], [[anesthesia]], and [[coma]].  Use in well-ventilated areas and use protective gloves while using.  Poisoning can occur from ingestion, inhalation, or absorption.
 
Long term application to the skin can cause [[defatting]].
 
==Medicine/Toxicology==
Isopropyl alcohol is about twice as toxic as [[ethanol]]. Isopropyl alcohol does not cause an [[anion gap]] [[acidosis]] (like [[ethanol]] or [[methanol]]).  It produces an elevated [[osmolal gap]], but generally no abnormal anion gap (though this may be seen as a result of [[hypotension]] and [[lactic acidosis]]).  Overdoses may cause a fruity odor on the breath as a result of its metabolism to give [[acetone]] (which is not further metabolised)<ref>Tiess, D: Z. ges. Hygiene 31, 530-531 (1985)</ref>.  While large quantities of isopropanol can be fatal if left untreated, it is not nearly as toxic as methanol or ethylene glycol.
 
==References==
<references/>
 
==External links==
* [http://www.bluerhinos.co.uk/molview/indv.php?id=16 Molview from bluerhinos.co.uk] See Propan-2-ol in 3D
* [http://physchem.ox.ac.uk/MSDS/PR/2-propanol.html Safety (MSDS) data for 2-propanol]
* [http://www.osha.gov/SLTC/healthguidelines/isopropylalcohol/recognition.html The US government's Occupational Safety and Health Administration's guidelines for isopropyl alcohol.]
 
{{Alcohols}}
{{Antiseptics and disinfectants}}
 
[[Category:Alcohols]]
[[Category:Alcohol solvents]]
[[Category:Alcohol solvents]]
[[Category:Oxygenates]]
[[Category:Oxygenates]]
 
[[Category:Antiseptics]]
[[da:Isopropylalkohol]]
[[Category:Disinfectants]]
[[de:2-Propanol]]
[[el:Ισοπροπανόλη]]
[[es:Alcohol isopropílico]]
[[fr:Isopropanol]]
[[hr:Izopropanol]]
[[it:2-propanolo]]
[[lv:Izopropanols]]
[[ms:Isopropanol]]
[[nl:2-propanol]]
[[ja:イソプロパノール]]
[[no:Isopropanol]]
[[pl:Alkohol izopropylowy]]
[[pt:Álcool isopropílico]]
[[ru:Изопропиловый спирт]]
[[sl:Izopropanol]]
[[fi:2-propanoli]]
{{jb1}}
{{WH}}
{{WikiDoc Sources}}

Latest revision as of 16:33, 20 August 2015

Isopropyl alcohol
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Disclaimer

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NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Isopropyl alcohol is an antiseptic that is FDA approved for the treatment of cuts, scrapes and minor muscular aches. Common adverse reactions include hypersensitivity.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

to decrease germs in minor cuts and scrapes. helps relieve minor muscular aches due to exertion.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Isopropyl alcohol in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Contraindications

There is limited information regarding Isopropyl alcohol Contraindications in the drug label.

Warnings

  • For external use only
  • Flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally
  • Ask a doctor before use if you have deep puncture wounds or serious burns
  • When using this product do not get into eyes or mucous membranes use only in a well-ventilated area.
  • Stop use and ask a doctor if condition persists or gets worse.
  • Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Isopropyl alcohol in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Isopropyl alcohol in the drug label.

Drug Interactions

There is limited information regarding Isopropyl alcohol Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isopropyl alcohol in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Isopropyl alcohol during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Isopropyl alcohol with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific gender populations.

Race

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Isopropyl alcohol in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Isopropyl alcohol in patients who are immunocompromised.

Administration and Monitoring

Administration

Monitoring

There is limited information regarding Monitoring of Isopropyl alcohol in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Isopropyl alcohol in the drug label.

Overdosage

There is limited information regarding Isopropyl alcohol overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox UNNumberTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox pKaTemplate:Chembox RefractIndexTemplate:Chembox ViscosityTemplate:Chembox DipoleTemplate:Chembox MainHazardsTemplate:Chembox GHSPictogramsTemplate:Chembox GHSSignalWordTemplate:Chembox HPhrasesTemplate:Chembox PPhrasesTemplate:Chembox NFPATemplate:Chembox FlashPtTemplate:Chembox ExploLimitsTemplate:Chembox TLVTemplate:Chembox Lethal amounts (set)Template:Chembox NIOSH (set)Template:Chembox Supplement
Template:Chembox header2 | Isopropyl alcohol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG
UNII
Properties
C3H8O
Molar mass 60.10 g·mol−1
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Isopropyl alcohol Mechanism of Action in the drug label.

Structure

There is limited information regarding Isopropyl alcohol Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Isopropyl alcohol in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Isopropyl alcohol in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Isopropyl alcohol in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Isopropyl alcohol in the drug label.

How Supplied

There is limited information regarding Isopropyl alcohol How Supplied in the drug label.

Storage

There is limited information regarding Isopropyl alcohol Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

  • Apply to skin directly or with clean gauze, cotton or swab.
  • For rubbing, apply liberally and rub with hands.

Precautions with Alcohol

  • Alcohol-Isopropyl alcohol interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • ISOPROPYL RUBBING ALCOHOL®[4]

Look-Alike Drug Names

There is limited information regarding Isopropyl alcohol Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Reeve, W.; Erikson, C.M.; Aluotto, P.F. (1979). "A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides". Can. J. Chem. 57 (20): 2747. doi:10.1139/v79-444.
  2. ↑ 2.0 2.1 Yaws, C.L. (1999). Chemical Properties Handbook. McGraw-Hill. ISBN 0-07-073401-1.
  3. ↑ Template:PGCH
  4. ↑ "ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid".

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