Ischemic colitis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
There are no specific blood tests for ischemic colitis, but an [[elevated white blood cell count]] may be present. Other laboratory findings in ischemic colitis include electrolyte and renal abnormalities secondary to dehydration, metabolic acidosis, and lactate level may be elevated due to any tissue hypoxia. | There are no specific [[Blood test|blood tests]] for ischemic colitis, but an [[elevated white blood cell count]] may be present. Other [[Medical laboratory|laboratory]] findings in ischemic colitis include [[Electrolyte disturbance|electrolyte]] and [[Kidney|renal]] abnormalities secondary to [[dehydration]], [[metabolic acidosis]], and [[Lactic acid|lactate]] level may be elevated due to any [[Tissue (biology)|tissue]] [[Hypoxemia|hypoxia]]. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
The laboratory findings for ischemic colitis are as follows:<ref name="SunMaykel2007">{{cite journal|last1=Sun|first1=Mark|last2=Maykel|first2=Justin|title=Ischemic Colitis|journal=Clinics in Colon and Rectal Surgery|volume=20|issue=1|year=2007|pages=005–012|issn=1531-0043|doi=10.1055/s-2007-970194}}</ref> <ref name="HuguierBarrier2006">{{cite journal|last1=Huguier|first1=Michel|last2=Barrier|first2=Alain|last3=Boelle|first3=Pierre Y.|last4=Houry|first4=Sydney|last5=Lacaine|first5=Francois|title=Ischemic colitis|journal=The American Journal of Surgery|volume=192|issue=5|year=2006|pages=679–684|issn=00029610|doi=10.1016/j.amjsurg.2005.09.018}}</ref><ref name="pmid8209931">{{cite journal| author=Murray MJ, Gonze MD, Nowak LR, Cobb CF| title=Serum D(-)-lactate levels as an aid to diagnosing acute intestinal ischemia. | journal=Am J Surg | year= 1994 | volume= 167 | issue= 6 | pages= 575-8 | pmid=8209931 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8209931 }} </ref> | The [[Medical laboratory|laboratory]] findings for ischemic colitis are as follows:<ref name="SunMaykel2007">{{cite journal|last1=Sun|first1=Mark|last2=Maykel|first2=Justin|title=Ischemic Colitis|journal=Clinics in Colon and Rectal Surgery|volume=20|issue=1|year=2007|pages=005–012|issn=1531-0043|doi=10.1055/s-2007-970194}}</ref><ref name="HuguierBarrier2006">{{cite journal|last1=Huguier|first1=Michel|last2=Barrier|first2=Alain|last3=Boelle|first3=Pierre Y.|last4=Houry|first4=Sydney|last5=Lacaine|first5=Francois|title=Ischemic colitis|journal=The American Journal of Surgery|volume=192|issue=5|year=2006|pages=679–684|issn=00029610|doi=10.1016/j.amjsurg.2005.09.018}}</ref><ref name="pmid8209931">{{cite journal| author=Murray MJ, Gonze MD, Nowak LR, Cobb CF| title=Serum D(-)-lactate levels as an aid to diagnosing acute intestinal ischemia. | journal=Am J Surg | year= 1994 | volume= 167 | issue= 6 | pages= 575-8 | pmid=8209931 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8209931 }} </ref> | ||
*Mild leukocytosis with a left shift | *Mild [[leukocytosis]] with a left shift | ||
*Electrolyte and renal abnormalities secondary to dehydration | *[[Electrolyte disturbance|Electrolyte]] and [[Kidney|renal]] abnormalities secondary to dehydration | ||
*Metabolic acidosis may be present | *[[Metabolic acidosis]] may be present | ||
*Lactate level may be elevated due to any tissue hypoxia | *[[Lactic acid|Lactate]] level may be elevated due to any [[Tissue (biology)|tissue]] [[Hypoxemia|hypoxia]] | ||
**Sensitivity of 82% and a specificity of 87% in predicting early colonic ischemia. | **[[Sensitivity (tests)|Sensitivity]] of 82% and a [[Specificity (tests)|specificity]] of 87% in predicting early colonic [[ischemia]]. | ||
*The sensitivity of tests among 73 patients were: | *The sensitivity of tests among 73 patients were: | ||
**[[Elevated white blood cell count]] more than 15,000/mm<sup>3</sup> in 20 patients (27%) | **[[Elevated white blood cell count]] more than 15,000/mm<sup>3</sup> in 20 patients (27%) | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | {{WH}} | ||
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[[Category:Gastroenterology]] | |||
[[Category:Medicine]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 14:37, 5 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
There are no specific blood tests for ischemic colitis, but an elevated white blood cell count may be present. Other laboratory findings in ischemic colitis include electrolyte and renal abnormalities secondary to dehydration, metabolic acidosis, and lactate level may be elevated due to any tissue hypoxia.
Laboratory Findings
The laboratory findings for ischemic colitis are as follows:[1][2][3]
- Mild leukocytosis with a left shift
- Electrolyte and renal abnormalities secondary to dehydration
- Metabolic acidosis may be present
- Lactate level may be elevated due to any tissue hypoxia
- Sensitivity of 82% and a specificity of 87% in predicting early colonic ischemia.
- The sensitivity of tests among 73 patients were:
- Elevated white blood cell count more than 15,000/mm3 in 20 patients (27%)
- The serum bicarbonate level was less than 24 mmol/L in 26 patients (36%)
References
- ↑ Sun, Mark; Maykel, Justin (2007). "Ischemic Colitis". Clinics in Colon and Rectal Surgery. 20 (1): 005–012. doi:10.1055/s-2007-970194. ISSN 1531-0043.
- ↑ Huguier, Michel; Barrier, Alain; Boelle, Pierre Y.; Houry, Sydney; Lacaine, Francois (2006). "Ischemic colitis". The American Journal of Surgery. 192 (5): 679–684. doi:10.1016/j.amjsurg.2005.09.018. ISSN 0002-9610.
- ↑ Murray MJ, Gonze MD, Nowak LR, Cobb CF (1994). "Serum D(-)-lactate levels as an aid to diagnosing acute intestinal ischemia". Am J Surg. 167 (6): 575–8. PMID 8209931.