Irregular lesion: Difference between revisions
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==Overview== | ==Overview== | ||
The appearence of irregular lesions with intraluminal filling defects and contrast staining may indicate a fissured atherosclerotic plaque with adherent thrombus.<ref name="Davies-1991">{{Cite journal | last1 = Davies | first1 = SW. | last2 = Marchant | first2 = B. | last3 = Lyons | first3 = JP. | last4 = Timmis | first4 = AD. | last5 = Rothman | first5 = MT. | last6 = Layton | first6 = CA. | last7 = Balcon | first7 = R. | title = Irregular coronary lesion morphology after thrombolysis predicts early clinical instability. | journal = J Am Coll Cardiol | volume = 18 | issue = 3 | pages = 669-74 | month = Sep | year = 1991 | doi = | PMID = 1869729 }}</ref> | The appearence of irregular lesions with intraluminal filling defects and contrast staining is detected by [[coronary angiography]] and may indicate a fissured [[Atherosclerosis|atherosclerotic plaque]] with adherent [[thrombus]].<ref name="Davies-1991">{{Cite journal | last1 = Davies | first1 = SW. | last2 = Marchant | first2 = B. | last3 = Lyons | first3 = JP. | last4 = Timmis | first4 = AD. | last5 = Rothman | first5 = MT. | last6 = Layton | first6 = CA. | last7 = Balcon | first7 = R. | title = Irregular coronary lesion morphology after thrombolysis predicts early clinical instability. | journal = J Am Coll Cardiol | volume = 18 | issue = 3 | pages = 669-74 | month = Sep | year = 1991 | doi = | PMID = 1869729 }}</ref> | ||
==Definition== | ==Definition== | ||
Revision as of 19:11, 21 November 2013
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Coronary Angiography | |
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General Principles | |
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Anatomy & Projection Angles | |
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Normal Anatomy | |
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Anatomic Variants | |
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Projection Angles | |
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Epicardial Flow & Myocardial Perfusion | |
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Epicardial Flow | |
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Myocardial Perfusion | |
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Lesion Complexity | |
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ACC/AHA Lesion-Specific Classification of the Primary Target Stenosis | |
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Lesion Morphology | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The appearence of irregular lesions with intraluminal filling defects and contrast staining is detected by coronary angiography and may indicate a fissured atherosclerotic plaque with adherent thrombus.[1]
Definition
A stenosis is classified as having irregular contour if the vascular margin is rough or has a "sawtooth" appearance.[2]
Pathophysiology
Grading of Lesion Irregularity
- Grade 0: Smooth – no irregularity.
- Grade 1: Mildly Irregular – lesion has an indistinct lumen edge.
- Grade 2: Sawtoothed/Grossly Irregular – lesion has defined jagged or “sawtoothed” lumen edges.
Clinical Significance
Example
References
- ↑ Davies, SW.; Marchant, B.; Lyons, JP.; Timmis, AD.; Rothman, MT.; Layton, CA.; Balcon, R. (1991). "Irregular coronary lesion morphology after thrombolysis predicts early clinical instability". J Am Coll Cardiol. 18 (3): 669–74. PMID 1869729. Unknown parameter
|month=ignored (help) - ↑ Ellis, SG.; Vandormael, MG.; Cowley, MJ.; DiSciascio, G.; Deligonul, U.; Topol, EJ.; Bulle, TM. (1990). "Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Multivessel Angioplasty Prognosis Study Group". Circulation. 82 (4): 1193–202. PMID 2401060. Unknown parameter
|month=ignored (help)