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| __NOTOC__
| | #REDIRECT [[Coronary artery irregularity]] |
| {{Coronary angiography2}}
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| {{CMG}}
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| ==Overview==
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| The appearence of irregular lesions with intraluminal filling defects and contrast staining is detected by [[coronary angiography]] and may indicate a fissured [[Atherosclerosis|atherosclerotic plaque]] with adherent [[thrombus]].<ref name="Davies-1991">{{Cite journal | last1 = Davies | first1 = SW. | last2 = Marchant | first2 = B. | last3 = Lyons | first3 = JP. | last4 = Timmis | first4 = AD. | last5 = Rothman | first5 = MT. | last6 = Layton | first6 = CA. | last7 = Balcon | first7 = R. | title = Irregular coronary lesion morphology after thrombolysis predicts early clinical instability. | journal = J Am Coll Cardiol | volume = 18 | issue = 3 | pages = 669-74 | month = Sep | year = 1991 | doi = | PMID = 1869729 }}</ref>
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| ==Definition==
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| A stenosis is classified as having '''irregular contour''' if the vascular margin is rough or has a "sawtooth" appearance.<ref name="Ellis-1990">{{Cite journal | last1 = Ellis | first1 = SG. | last2 = Vandormael | first2 = MG. | last3 = Cowley | first3 = MJ. | last4 = DiSciascio | first4 = G. | last5 = Deligonul | first5 = U. | last6 = Topol | first6 = EJ. | last7 = Bulle | first7 = TM. | title = Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Multivessel Angioplasty Prognosis Study Group. | journal = Circulation | volume = 82 | issue = 4 | pages = 1193-202 | month = Oct | year = 1990 | doi = | PMID = 2401060 }}</ref>
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| ==Pathophysiology==
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| ==Grading of Lesion Irregularity==
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| * Grade 0: Smooth – no irregularity.
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| * Grade 1: Mildly Irregular – lesion has an indistinct lumen edge.
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| * Grade 2: Sawtoothed/Grossly Irregular – lesion has defined jagged or “sawtoothed” lumen edges.
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| ==Clinical Significance==
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| ==Example==
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| ==References==
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| {{Reflist|2}}
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| [[Category:Angiopedia]]
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| [[Category:Cardiology]]
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