Intussusception pathophysiology

Intussusception Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Gross Pathology

Intussusception is caused by part of the intestine being pulled inward into itself. This can block the passage of food through the intestine. If the blood supply is cut off, the segment of intestine pulled inside can die.

The pressure created by the walls of the intestine pressing together causes:

• Decreased blood flow
• Irritation
• Swelling

The intestine can die, and the patient can have significant bleeding. If a hole occurs, infection, shock, and dehydration can take place very rapidly.