Intracerebral metastases medical therapy

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Intracerebral metastases Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]


Overview

Medical Therapy

Symptomatic Treatment

  • Corticosteroids are given to limit the effects of peritumoral edema.[1] Hyperosmolar agents (eg mannitol) can be given to decrease ICP and anticonvulsants are given to prevent seizures. Recently, methylphenidate and donepezil have been used to improve cognition, mood and quality of life.

Therapeutic

Radiation Therapy

  • The most widely used treatment for patients with multiple brain metastases is WBRT (whole brain external beam radiotherapy).[1]
  • Stereotactic radiosurgery is done for smaller masses.

References

  1. 1.0 1.1 Khuntia, Deepak (2015). "Contemporary Review of the Management of Brain Metastasis with Radiation". Advances in Neuroscience. 2015: 1–13. doi:10.1155/2015/372856. ISSN 2356-6787.


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