Intracerebral metastases history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

When evaluating a patient for intracerebral metastases, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include review of the primary tumor (lung, brain, melanoma, colorectal cancer).[1][2][3] 60-75% of patients with intracerebral metastases may be asymptomatic.[4] Symptoms of intracerebral metastases include headache, seizures, visual disturbances, cognitive dysfunction, paresthesia, and muscle weakness.[4][5][6][7]

History

When evaluating a patient for intracerebral metastases, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and past medical history review. Other specific areas of focus when obtaining the history include:[1][2][3]

  • Review of the primary tumor (lung, brain, melanoma, colorectal cancer)

Symptoms

  • 60-75% of patients with intracerebral metastases may be asymptomatic.[4]
  • Symptoms of intracerebral metastases include:[4][5][6][7]

References

  1. 1.0 1.1 Causes of brain metastasis. Wikipedia 2015. https://en.wikipedia.org/wiki/Brain_metastasis. Accessed on November 9, 2015
  2. 2.0 2.1 Epidemiology of brain metastasis. Dr Bruno Di Muzio and Dr Trent Orton et al. Radiopaedia 2015. http://radiopaedia.org/articles/brain-metastases. Accessed on November 9, 2015
  3. 3.0 3.1 Rahmathulla, Gazanfar; Toms, Steven A.; Weil, Robert J. (2012). "The Molecular Biology of Brain Metastasis". Journal of Oncology. 2012: 1–16. doi:10.1155/2012/723541. ISSN 1687-8450.
  4. 4.0 4.1 4.2 4.3 Clinical presentation of brain metastases. Dr Bruno Di Muzio and Dr Trent Orton et al. Radiopaedia 2015. http://radiopaedia.org/articles/brain-metastases. Accessed on November 9, 2015
  5. 5.0 5.1 Symptoms of brain metastases. Wikipedia 2015. https://en.wikipedia.org/wiki/Brain_metastasis. Accessed on November 9, 2015
  6. 6.0 6.1 Symptoms of metastatic brain tumor. US national library of medicine 2015. https://www.nlm.nih.gov/medlineplus/ency/article/000769.htm. Accessed on November 9, 2015
  7. 7.0 7.1 Andrew B. Lassman & Lisa M. DeAngelis (2003). "Brain metastases". Neurologic clinics. 21 (1): 1–23. PMID 12690643. Unknown parameter |month= ignored (help)


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