Interstitial nephritis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
==Blood tests== | |||
About 23% of patients have [[eosinophilia]]<ref name="pmid14671029">.</ref>. | |||
==Urinary findings== | |||
Urinary findings include: | |||
* [[Eosinophiluria]]: [[sensitivity (tests)|sensitivity]] is 67% and [[specificity (tests)|specificity]] is 83% <ref name="pmid11473672">.</ref><ref name="pmid11020015">{{cite journal |author=Schwarz A, Krause P, Kunzendorf U, Keller F, Distler A |title=The outcome of acute interstitial nephritis risk factors for the transition from acute to chronic interstitial nephritis |journal=Clin Nephrol |volume=54 |issue=3 |pages=179-90 |year=2000 |pmid=11020015}}</ref>. The [[sensitivity (tests)|sensitivity]] is higher in patients with interstitial nephritis induced by [[methicillin]] or when the Hansel's stain is used. | |||
* [[Isosthenuria]] <ref name="pmid3769228">{{cite journal |author=Lins R, Verpooten G, De Clerck D, De Broe M |title=Urinary indices in acute interstitial nephritis |journal=Clin Nephrol |volume=26 |issue=3 |pages=131-3 |year=1986 |pmid=3769228}}</ref> | |||
==Gallium scan== | |||
The [[sensitivity (tests)|sensitivity]] of an abnormal [[gallium scan]] has been reported to range from 60%<ref name="pmid6864309">{{cite journal |author=Graham G, Lundy M, Moreno A |title=Failure of Gallium-67 scintigraphy to identify reliably noninfectious interstitial nephritis: concise communication |journal=J Nucl Med |volume=24 |issue=7 |pages=568-70 |year=1983 |pmid=6864309}}</ref> to 100%<ref name="pmid3862487">{{cite journal |author=Linton A, Richmond J, Clark W, Lindsay R, Driedger A, Lamki L |title=Gallium67 scintigraphy in the diagnosis of acute renal disease |journal=Clin Nephrol |volume=24 |issue=2 |pages=84-7 |year=1985 |pmid=3862487}}</ref>. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 18:41, 27 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Blood tests
About 23% of patients have eosinophilia[1].
Urinary findings
Urinary findings include:
- Eosinophiluria: sensitivity is 67% and specificity is 83% [2][3]. The sensitivity is higher in patients with interstitial nephritis induced by methicillin or when the Hansel's stain is used.
- Isosthenuria [4]
Gallium scan
The sensitivity of an abnormal gallium scan has been reported to range from 60%[5] to 100%[6].
References
- ↑ .
- ↑ .
- ↑ Schwarz A, Krause P, Kunzendorf U, Keller F, Distler A (2000). "The outcome of acute interstitial nephritis risk factors for the transition from acute to chronic interstitial nephritis". Clin Nephrol. 54 (3): 179–90. PMID 11020015.
- ↑ Lins R, Verpooten G, De Clerck D, De Broe M (1986). "Urinary indices in acute interstitial nephritis". Clin Nephrol. 26 (3): 131–3. PMID 3769228.
- ↑ Graham G, Lundy M, Moreno A (1983). "Failure of Gallium-67 scintigraphy to identify reliably noninfectious interstitial nephritis: concise communication". J Nucl Med. 24 (7): 568–70. PMID 6864309.
- ↑ Linton A, Richmond J, Clark W, Lindsay R, Driedger A, Lamki L (1985). "Gallium67 scintigraphy in the diagnosis of acute renal disease". Clin Nephrol. 24 (2): 84–7. PMID 3862487.