Impetigo causes: Difference between revisions

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__NOTOC__
__NOTOC__
{{‪Impetigo‬}}
{{‪Impetigo‬}}
{{CMG}}
{{CMG}}; {{AE}} {{USAMA}}


==Overview==
==Overview==
Impetigo is usually caused by ''[[Staphylococcus aureus]]'', it may also be caused by the same [[streptococcus]] strain that causes [[strep throat]], ''[[Streptococcus pyogenes]]''.
Impetigo is usually caused by ''[[Staphylococcus aureus]].'' [[Streptococci]] (e.g. ''[[Streptococcus pyogenes]]'') have been associated with the non-bullous form of impetigo and [[ecthyma]].[[Streptococci]] can either infect individually or co-infect with [[Staphylococcus aureus]]. Non-bullous impetigo makes 70% of all the caess of impetigo.<ref name="pmid7899177">{{cite journal| author=Darmstadt GL, Lane AT| title=Impetigo: an overview. | journal=Pediatr Dermatol | year= 1994 | volume= 11 | issue= 4 | pages= 293-303 | pmid=7899177 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7899177  }} </ref><ref name="pmid2244610">{{cite journal| author=Demidovich CW, Wittler RR, Ruff ME, Bass JW, Browning WC| title=Impetigo. Current etiology and comparison of penicillin, erythromycin, and cephalexin therapies. | journal=Am J Dis Child | year= 1990 | volume= 144 | issue= 12 | pages= 1313-5 | pmid=2244610 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2244610  }} </ref><ref name=":0" /><ref name="pmid17390597">{{cite journal| author=Cole C, Gazewood J| title=Diagnosis and treatment of impetigo. | journal=Am Fam Physician | year= 2007 | volume= 75 | issue= 6 | pages= 859-64 | pmid=17390597 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17390597  }} </ref>


==Causes==
==Causes==
According to the [[American Academy of Family Physicians]] - "Nonbullous impetigo was previously thought to be a group A streptococcal process and bullous impetigo was primarily thought to be caused by ''S. aureus''. Studies now indicate that both forms of impetigo are primarily caused by ''S. aureus'' with Streptococcus usually being involved in the nonbullous form"<ref>{{cite journal |author=Stulberg DL, Penrod MA, Blatny RA |title=Common bacterial skin infections |journal=American family physician |volume=66 |issue=1 |pages=119-24 |year=2002 |pmid=12126026 |doi= |url=http://www.aafp.org/afp/20020701/119.html}}</ref>
It was previously believed  that non-bullous impetigo is caused by [[group A streptococci]] whereas ''[[Staphylococcus aureus]]'' causes the bullous subtype of impetigo. Both bullous and non-bullous subtypes of impetigo are now understood to be primarily caused by ''[[Staphylococcus aureus|S. aureus]].'' [[Streptococci]] have been associated with the non-bullous form and [[ecthyma]].<ref name=":0">{{cite journal |author=Stulberg DL, Penrod MA, Blatny RA |title=Common bacterial skin infections |journal=American family physician |volume=66 |issue=1 |pages=119-24 |year=2002 |pmid=12126026 |doi= |url=http://www.aafp.org/afp/20020701/119.html}}</ref><ref name="pmid22187567">{{cite journal| author=Kikuta H, Shibata M, Nakata S, Yamanaka T, Sakata H, Akizawa K et al.| title=Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan. | journal=Int J Pediatr | year= 2011 | volume= 2011 | issue=  | pages= 143872 | pmid=22187567 | doi=10.1155/2011/143872 | pmc=3236481 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22187567  }} </ref><ref name="pmid21430094">{{cite journal| author=Shi D, Higuchi W, Takano T, Saito K, Ozaki K, Takano M et al.| title=Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. | journal=J Clin Microbiol | year= 2011 | volume= 49 | issue= 5 | pages= 1972-4 | pmid=21430094 | doi=10.1128/JCM.01742-10 | pmc=3122639 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21430094  }} </ref><ref name="pmid24655406">{{cite journal| author=Jenney A, Holt D, Ritika R, Southwell P, Pravin S, Buadromo E et al.| title=The clinical and molecular epidemiology of Staphylococcus aureus infections in Fiji. | journal=BMC Infect Dis | year= 2014 | volume= 14 | issue=  | pages= 160 | pmid=24655406 | doi=10.1186/1471-2334-14-160 | pmc=3998116 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24655406  }} </ref>
 
===Common causes===
The common causes of impetigo include:<ref name="pmid27617460">{{cite journal| author=Cohen PR| title=Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy. | journal=Dermatol Online J | year= 2016 | volume= 22 | issue= 4 | pages=  | pmid=27617460 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27617460  }} </ref><ref name="pmid27458596">{{cite journal| author=Duggal SD, Bharara T, Jena PP, Kumar A, Sharma A, Gur R et al.| title=Staphylococcal bullous impetigo in a neonate. | journal=World J Clin Cases | year= 2016 | volume= 4 | issue= 7 | pages= 191-4 | pmid=27458596 | doi=10.12998/wjcc.v4.i7.191 | pmc=4945591 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27458596  }} </ref><ref name="pmid15963289">{{cite journal| author=Moran GJ, Amii RN, Abrahamian FM, Talan DA| title=Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. | journal=Emerg Infect Dis | year= 2005 | volume= 11 | issue= 6 | pages= 928-30 | pmid=15963289 | doi=10.3201/eid1106.040641 | pmc=3367577 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15963289  }} </ref><ref name="pmid16361729">{{cite journal| author=Kuniyuki S, Nakano K, Maekawa N, Suzuki S| title=Topical antibiotic treatment of impetigo with tetracycline. | journal=J Dermatol | year= 2005 | volume= 32 | issue= 10 | pages= 788-92 | pmid=16361729 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16361729  }} </ref>
*''[[Staphylococcus aureus]]''
**[[Methicillin-resistant staphylococcus aureus|Methicillin-resistant ''Staphylococcus aureus'']] ([[Methicillin-resistant staphylococcus aureus|MRSA]])
**Gentamicin-resistant [[Staphylococcus aureus]]
 
* ''[[Streptococcus pyogenes]]''
 
=== Bullous Impetigo ===
* ''[[Staphylococcus aureus]]''
 
=== Non-bullous Impetigo ===
* ''[[Staphylococcus aureus]]''
* [[Group A beta-hemolytic streptococci|Group A, beta-hemolytic ''Streptococcus'']] ([[Streptococcus pyogenes|''Streptococcus pyogenes'']])
 
=== Ecthyma ===
* [[Group A beta-hemolytic streptococci|Group A, beta-hemolytic ''Streptococcus'']] ([[Streptococcus pyogenes|''Streptococcus pyogenes'']])


===Drug Induced===
===Drug Induced===
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{{Reflist|2}}
{{Reflist|2}}


[[Category:Infectious disease]]
 
{{WH}}
{{WS}}
 
[[Category:Disease]]
[[Category:Disease]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Infectious skin diseases]]
[[Category:Infectious skin diseases]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Primary care]]
[[Category:Emergency mdicine]]
 
[[Category:Up-To-Date]]
{{WH}}
[[Category:Infectious disease]]
{{WS}}
[[Category:Gynecology]]
[[Category:Urology]]

Latest revision as of 22:21, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

Overview

Impetigo is usually caused by Staphylococcus aureus. Streptococci (e.g. Streptococcus pyogenes) have been associated with the non-bullous form of impetigo and ecthyma.Streptococci can either infect individually or co-infect with Staphylococcus aureus. Non-bullous impetigo makes 70% of all the caess of impetigo.[1][2][3][4]

Causes

It was previously believed that non-bullous impetigo is caused by group A streptococci whereas Staphylococcus aureus causes the bullous subtype of impetigo. Both bullous and non-bullous subtypes of impetigo are now understood to be primarily caused by S. aureus. Streptococci have been associated with the non-bullous form and ecthyma.[3][5][6][7]

Common causes

The common causes of impetigo include:[8][9][10][11]

Bullous Impetigo

Non-bullous Impetigo

Ecthyma

Drug Induced

References

  1. Darmstadt GL, Lane AT (1994). "Impetigo: an overview". Pediatr Dermatol. 11 (4): 293–303. PMID 7899177.
  2. Demidovich CW, Wittler RR, Ruff ME, Bass JW, Browning WC (1990). "Impetigo. Current etiology and comparison of penicillin, erythromycin, and cephalexin therapies". Am J Dis Child. 144 (12): 1313–5. PMID 2244610.
  3. 3.0 3.1 Stulberg DL, Penrod MA, Blatny RA (2002). "Common bacterial skin infections". American family physician. 66 (1): 119–24. PMID 12126026.
  4. Cole C, Gazewood J (2007). "Diagnosis and treatment of impetigo". Am Fam Physician. 75 (6): 859–64. PMID 17390597.
  5. Kikuta H, Shibata M, Nakata S, Yamanaka T, Sakata H, Akizawa K; et al. (2011). "Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan". Int J Pediatr. 2011: 143872. doi:10.1155/2011/143872. PMC 3236481. PMID 22187567.
  6. Shi D, Higuchi W, Takano T, Saito K, Ozaki K, Takano M; et al. (2011). "Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage". J Clin Microbiol. 49 (5): 1972–4. doi:10.1128/JCM.01742-10. PMC 3122639. PMID 21430094.
  7. Jenney A, Holt D, Ritika R, Southwell P, Pravin S, Buadromo E; et al. (2014). "The clinical and molecular epidemiology of Staphylococcus aureus infections in Fiji". BMC Infect Dis. 14: 160. doi:10.1186/1471-2334-14-160. PMC 3998116. PMID 24655406.
  8. Cohen PR (2016). "Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy". Dermatol Online J. 22 (4). PMID 27617460.
  9. Duggal SD, Bharara T, Jena PP, Kumar A, Sharma A, Gur R; et al. (2016). "Staphylococcal bullous impetigo in a neonate". World J Clin Cases. 4 (7): 191–4. doi:10.12998/wjcc.v4.i7.191. PMC 4945591. PMID 27458596.
  10. Moran GJ, Amii RN, Abrahamian FM, Talan DA (2005). "Methicillin-resistant Staphylococcus aureus in community-acquired skin infections". Emerg Infect Dis. 11 (6): 928–30. doi:10.3201/eid1106.040641. PMC 3367577. PMID 15963289.
  11. Kuniyuki S, Nakano K, Maekawa N, Suzuki S (2005). "Topical antibiotic treatment of impetigo with tetracycline". J Dermatol. 32 (10): 788–92. PMID 16361729.


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