Immunodeficiency: Difference between revisions

Jump to navigation Jump to search
mNo edit summary
 
m (Robot: Automated text replacement (-{{SIB}} + & -{{EH}} + & -{{EJ}} + & -{{Editor Help}} + & -{{Editor Join}} +))
Line 37: Line 37:
{{Immune_system}}
{{Immune_system}}
{{Immune disorders}}
{{Immune disorders}}
{{SIB}}
 


[[Category:Immune system disorders]]
[[Category:Immune system disorders]]

Revision as of 16:19, 9 August 2012

Immunodeficiency
ICD-10 D84.9
ICD-9 279.3
DiseasesDB 21506
MeSH D007153

WikiDoc Resources for Immunodeficiency

Articles

Most recent articles on Immunodeficiency

Most cited articles on Immunodeficiency

Review articles on Immunodeficiency

Articles on Immunodeficiency in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Immunodeficiency

Images of Immunodeficiency

Photos of Immunodeficiency

Podcasts & MP3s on Immunodeficiency

Videos on Immunodeficiency

Evidence Based Medicine

Cochrane Collaboration on Immunodeficiency

Bandolier on Immunodeficiency

TRIP on Immunodeficiency

Clinical Trials

Ongoing Trials on Immunodeficiency at Clinical Trials.gov

Trial results on Immunodeficiency

Clinical Trials on Immunodeficiency at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Immunodeficiency

NICE Guidance on Immunodeficiency

NHS PRODIGY Guidance

FDA on Immunodeficiency

CDC on Immunodeficiency

Books

Books on Immunodeficiency

News

Immunodeficiency in the news

Be alerted to news on Immunodeficiency

News trends on Immunodeficiency

Commentary

Blogs on Immunodeficiency

Definitions

Definitions of Immunodeficiency

Patient Resources / Community

Patient resources on Immunodeficiency

Discussion groups on Immunodeficiency

Patient Handouts on Immunodeficiency

Directions to Hospitals Treating Immunodeficiency

Risk calculators and risk factors for Immunodeficiency

Healthcare Provider Resources

Symptoms of Immunodeficiency

Causes & Risk Factors for Immunodeficiency

Diagnostic studies for Immunodeficiency

Treatment of Immunodeficiency

Continuing Medical Education (CME)

CME Programs on Immunodeficiency

International

Immunodeficiency en Espanol

Immunodeficiency en Francais

Business

Immunodeficiency in the Marketplace

Patents on Immunodeficiency

Experimental / Informatics

List of terms related to Immunodeficiency

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In medicine, immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent. Most cases of immunodeficiency are acquired ("secondary") but some people are born with defects in the immune system, or primary immunodeficiency. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone.

Primary immunodeficiency

A number of rare diseases feature a heightened susceptibility to infections from childhood onward. Many of these disorders are hereditary and are autosomal recessive or X-linked. There are over 80 recognised primary immunodeficiency syndromes; they are generally grouped by the part of the immune system that is malfunctioning, such as lymphocytes or granulocytes.[1]

The treatment of primary immunodeficiencies depends on the nature of the defect, and may involve antibody infusions, long-term antibiotics and (in certain cases) stem cell transplantation.

Acquired immunodeficiency

Immune deficiency may also be the result of particular external processes or diseases; the resultant state is called "secondary" or "acquired" immunodeficiency. Common causes for secondary immunodeficiency are malnutrition, aging and particular medications (e.g. chemotherapy, disease-modifying antirheumatic drugs, immunosuppressive drugs after organ transplants, glucocorticoids).

Many specific diseases directly or indirectly impair the immune system. This include many types of cancer, particularly those of the bone marrow and blood cells (leukemia, lymphoma, multiple myeloma), and certain chronic infections. Immunodeficiency is also the hallmark of acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency virus (HIV). HIV directly attacks the immune system.

References

  1. Rosen FS, Cooper MD, Wedgwood RJ (1995). "The primary immunodeficiencies". The New England Journal of Medicine. 333 (7): 431–40. doi:10.1056/NEJM199508173330707. PMID 7616993. Retrieved 2012-03-08. Unknown parameter |month= ignored (help)

ca:Immunodeficiència de:Immundefekt el:Ανοσολογική ανεπάρκεια he:כשל חיסוני

Template:WH Template:WS