Idrocilamide

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Idrocilamide
Clinical data
Trade namesTalval, Srilane, Relaxnova, Brolitène
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Topical
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
E number{{#property:P628}}
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Chemical and physical data
FormulaC11H13NO2
Molar mass191.226 g/mol
3D model (JSmol)
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Idrocilamide (trade names Talval, Srilane, Relaxnova, Brolitène[1][2]) is a medication with skeletal muscle relaxant[3] and anti-inflammatory actions[4] used as a topical cream to treat lumbago and other kinds of muscular pain;[5] it is available on prescription or over-the-counter[citation needed] in France and various other countries.[1]

Interactions

Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.[6][7]

References

  1. 1.0 1.1 Drugs.com: International Drug Names
  2. Drugfuture.com: Idrocilamide
  3. PMID 2085796 (PMID 2085796)
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  4. Bannwarth B, Le Huec JC, Vinçon G; et al. (December 1993). "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]". Rev Rhum Ed Fr (in French). 60 (12): 932–6. PMID 8012322.
  5. PMID 2140002 (PMID 2140002)
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  6. Carrillo JA, Benitez J (August 2000). "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clin Pharmacokinet. 39 (2): 127–53. doi:10.2165/00003088-200039020-00004. PMID 10976659.
  7. Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC (January 1980). "Inhibition by idrocilamide of the disposition of caffeine". Eur. J. Clin. Pharmacol. 17 (1): 37–43. doi:10.1007/bf00561675. PMID 7371698.

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