ITIH3

Inter-alpha (globulin) inhibitor H3
Identifiers
Symbols	ITIH3 ; H3P
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1669
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Inter-alpha (globulin) inhibitor H3, also known as ITIH3, is a human gene.

Further reading

• Jean L, Risler JL, Nagase T; et al. (1999). "The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?". FEBS Lett. 446 (1): 6–8. PMID 10100603.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Salier JP, Simon D, Rouet P; et al. (1992). "Homologous chromosomal locations of the four genes for inter-alpha-inhibitor and pre-alpha-inhibitor family in human and mouse: assignment of the ancestral gene for the lipocalin superfamily". Genomics. 14 (1): 83–8. PMID 1385302.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Enghild JJ, Salvesen G, Hefta SA; et al. (1991). "Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor". J. Biol. Chem. 266 (2): 747–51. PMID 1898736.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Salier JP, Diarra-Mehrpour M, Sesboue R; et al. (1988). "Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI". Proc. Natl. Acad. Sci. U.S.A. 84 (23): 8272–6. PMID 2446322.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Diarra-Mehrpour M, Bourguignon J, Sesboüé R; et al. (1989). "Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes". Eur. J. Biochem. 179 (1): 147–54. PMID 2465147.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Enghild JJ, Thøgersen IB, Pizzo SV, Salvesen G (1989). "Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan". J. Biol. Chem. 264 (27): 15975–81. PMID 2476436.CS1 maint: Multiple names: authors list (link)
• Diarra-Mehrpour M, Bourguignon J, Sarafan N; et al. (1994). "Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes". Biochim. Biophys. Acta. 1219 (2): 551–4. PMID 7522574.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bourguignon J, Diarra-Mehrpour M, Thiberville L; et al. (1993). "Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence". Eur. J. Biochem. 212 (3): 771–6. PMID 7681778.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Blom AM, Thuveson M, Fries E (1998). "Intracellular coupling of bikunin and the heavy chain of rat pre-alpha-inhibitor in COS-1 cells". Biochem. J. 328 ( Pt 1): 185–91. PMID 9359851.CS1 maint: Multiple names: authors list (link)
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Diarra-Mehrpour M, Sarafan N, Bourguignon J; et al. (1998). "Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage". J. Biol. Chem. 273 (41): 26809–19. PMID 9756925.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thuveson M, Fries E (1999). "Intracellular proteolytic processing of the heavy chain of rat pre-alpha-inhibitor. The COOH-terminal propeptide is required for coupling to bikunin". J. Biol. Chem. 274 (10): 6741–6. PMID 10037773.
• Bourguignon J, Borghi H, Sesboüé R; et al. (1999). "Immunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissue". J. Histochem. Cytochem. 47 (12): 1625–32. PMID 10567446.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thuveson M, Fries E (2000). "The low pH in trans-Golgi triggers autocatalytic cleavage of pre-alpha -inhibitor heavy chain precursor". J. Biol. Chem. 275 (40): 30996–1000. doi:10.1074/jbc.M002399200. PMID 10893227.
• Kato M, Seki N, Sugano S; et al. (2002). "Identification of sonic hedgehog-responsive genes using cDNA microarray". Biochem. Biophys. Res. Commun. 289 (2): 472–8. doi:10.1006/bbrc.2001.5976. PMID 11716497.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Paris S, Sesboüé R, Delpech B; et al. (2002). "Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains". Int. J. Cancer. 97 (5): 615–20. PMID 11807786.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)