Difference between revisions of "Hypothyroidism causes"

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(Less Common Causes)
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*[[Tsh deficiency]]
*[[Tsh deficiency]]
===Less Common Causes===
*Hypothyroidism can result from postpartum [[thyroiditis]], a condition that affects about 5% of all women within a year after giving birth.  The first phase is typically hyperthyroidism.  Then, the thyroid either returns to normal or a woman develops hypothyroidism.  Of those women who experience hypothyroidism associated with postpartum thyroiditis, one in five will develop permanent hypothyroidism requiring life-long treatment.
*Hypothyroidism can also result from sporadic inheritance, sometimes [[autosome|autosomal]] recessive.
*Temporary hypothyroidism can be due to the [[Wolff-Chaikoff effect]].
===Causes by Organ System===
===Causes by Organ System===

Revision as of 16:49, 10 March 2017

Hypothyroidism Main page

Patient Information



Primary hypothyroidism
Hashimoto's thyroiditis
Secondary hypothyroidism
Tertiary hypothyroidism

Differentiating different causes of hypothyroidism



History and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vignesh Ponnusamy, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.


Hypothyroidism is commonly caused by iodine deficiency, hashimoto's thyroiditis, and diseases that cause disruption in pituitary hormone production. Neoplasms can be a life threatening cause of hypothyroidism and require prompt diagnosis and differentiation to reduce morbidity.


Life Threatening Causes

Common Causes

Causes by Organ System

Cardiovascular Alström syndrome, Aneurysm of the internal carotid artery, Neutral lipid storage disease
Chemical/Poisoning Iodine 131, Iodine antenatal infection , Iron overload , Isolated tsh deficiency, Lithium, Potassium iodide
Dental No underlying causes
Dermatologic Dermatosclerosis
Drug Side Effect Aminoglutethimide, Amiodarone, Antithyroid drugs, Atezolizumab, Axitinib, Bexarotene, Bromide , Carbimazole, Catch 22 , Ed-in-sol, Ethionamide, Femiron, Feosol, Feostat, Feratab, Fer-gen-sol, Fergon, Fer-in-sol, Ferrex, Hytinic, Icar, Interferon alfacon-1, Interferon alpha, Interferon-alfa, Interleukin-2, Ircon, Methimazole, Mitotane, Nephro-fer, Niferex, Nivolumab, Nu-iron, Oxcarbazepine, Para-amino salicylic acid, Peginterferon beta-1a, Pegylated interferon alfa-2b, Pembrolizumab, Perchlorate, Pergolide, Phenytoin and levothyroxine interaction, Pramipexole, Propylthiouracil, Slow-fe, Sorafenib, Thionamides, Thyroid and cholestyramine interaction, Tiagabine, Tocilizumab, Tositumomab iodine-131, Ttf-1, Ttf-2, Tyrosine kinase inhibitors, Vitron-c
Ear Nose Throat Bilateral abductor vocal cord paralysis syndrome 
Endocrine Abnormal maternal iodine levels, Acth deficiency, Antithyroid drugs, Apeced syndrome, Autoimmune polyendocrine syndrome type 3, Autoimmune thyroiditis, Brain-lung-thyroid syndrome, Central hypothyroidism, Chronic autoimmune thyroiditis, Combined pituitary hormone deficiency 1 (pou1f1 gene), Combined pituitary hormone deficiency 2 (prop1 gene), Combined pituitary hormone deficiency 3 (lhx gene), Congenital disorder of glycosylation type 1a , Congenital disorder of glycosylation type 1h , Congenital thyroid dysgenesis, Cretinism athyreotic , De quervain thyroiditis, Deficiency of pit1, Dopamine, Empty sella, Escamilla-lisser syndrome , Fibrous thyroiditis, Goiter , Graves disease , Hashimoto's thyroiditis, Hemochromatosis, Hyperthyroidism , Hypoadrenocorticism , Hypomelia , Hypopituitarism, Hypothalamic dysfunction , Hypothyroidism, Iodine deficiency, Iodine excess, Kaplowitz-bodurtha syndrome , Lymphocytic hypophysitis, Lymphocytic thyroiditis, Lymphomatous thyroiditis , Multiple endocrine abnormalities , Panhypopituitarism, Peripheral thyroid gland disorder resistance, Pituitary adenoma, Pituitary apoplexy, Pituitary cancer , Pituitary dwarfism type 3, Pituitary dysfunction , Polyendocrinopathy, Polyglandular disorders, Postpartum thyroiditis , Primary hypothyroidism, Pseudohypoparathyroidism type 1a, Rathke's cleft cyst, Reidel's thyroiditis, Resistance to thyroid hormone , Retinohepatoendocrinologic syndrome , Riedel syndrome , Secondary hypothyroidism, Sheehan syndrome, Silent thyroiditis, Subacute granulomatous thyroiditis, Subacute lymphocytic thyroiditis, Subacute thyroiditis, Subtotal thyroidectomy, Supprative thyroiditis, Thyreostatic therapy, Thyroid dysgenesis , Thyroid dyshormonogenesis , Thyroid ectopy, Thyroid hormone resistance , Thyroid stimulating hormone deficiency, Thyroidectomy, Thyroiditis, Trh deficiency, Tsh deficiency
Environmental No underlying causes
Gastroenterologic Diarrhea, Enteropathy, Retinohepatoendocrinologic syndrome 
Genetic 17-beta-hydroxysteroid dehydrogenase iii deficiency , Abnormal maternal iodine levels, Acth deficiency, Alström syndrome, Bamforth syndrome , Bangstad syndrome , Cdg syndrome type 1a , Chromosome 1, 1p36 deletion syndrome , Chromosome 10, monosomy 10p , Chromosome 10p deletion syndrome, Chromosome 12 ring syndrome , Chromosome 15q duplication syndrome , Chromosome 15q, trisomy , Chromosome 2 trisomy syndrome , Chromosome 6, trisomy 6q , Chromosome 6q duplication syndrome , Combined pituitary hormone deficiency 1 (pou1f1 gene), Combined pituitary hormone deficiency 2 (prop1 gene), Combined pituitary hormone deficiency 3 (lhx gene), Congenital disorder of glycosylation type 1a , Congenital disorder of glycosylation type 1h , Congenital thyroid dysgenesis, Cystinosis, Deficiency of pit1, Digeorge syndrome, Down syndrome, Emanuel syndrome, Ipex syndrome, Johanson-blizzard syndrome , Kaplowitz-bodurtha syndrome , Langerhans cell histiocytosis, Monosomy 1p36 , Mutations , Ohdo syndrome, Pax8, Pendred's syndrome , Poems syndrome, Septo-optic dysplasia, Turner syndrome, Velocardiofacial syndrome , Vilanova-canadeli syndrome , Wolfram syndrome 2 , Zadik barak levin syndrome 
Hematologic Diabetes insipidus, Diabetes mellitus, Hemochromatosis, Hemocyte, Iodine deficiency, Iodine excess, Iron overload , Isolated tsh deficiency, Maternal antibody, Subarachnoid hemorrhage
Iatrogenic Iatrogenic, Neck radiotherapy, Neck surgery, Radiation therapy, Radioactive iodine therapy, Subtotal thyroidectomy, Supprative thyroiditis, Thyroidectomy
Infectious Disease Iodine antenatal infection , Mycoses, Rathke's cleft cyst, Syphilis, Tuberculosis
Musculoskeletal/Orthopedic Bilateral abductor vocal cord paralysis syndrome 
Neurologic Aneurysm of the internal carotid artery, Brain-lung-thyroid syndrome, Craniopharyngioma, Dopamine, Down syndrome, Microcephaly , Microphthalmia syndromic, Neurosarcoidosis , Subarachnoid hemorrhage
Nutritional/Metabolic Diabetes insipidus, Diabetes mellitus, Diarrhea, Obesity
Obstetric/Gynecologic Neonatal illness, Sheehan syndrome
Oncologic Craniopharyngioma, Glioma, Hypomelia , Meningioma, Metastasis, Neoplastic, Pituitary adenoma, Pituitary apoplexy, Pituitary cancer 
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Amyloidosis, Tuberculosis
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Amyloidosis, Anti-tsh receptor antibodies, Apeced syndrome, Autoimmune disorders, Autoimmune enteropathy, Autoimmune polyendocrine syndrome type 3, Autoimmune thyroiditis, Chronic autoimmune thyroiditis, Dermatosclerosis, Fibrous thyroiditis, Graves disease , Immune dysregulation , Kashin-bek disease , Langerhans cell histiocytosis, Neurosarcoidosis , Rheumatoid arthritis, Sarcoidosis, Scleroderma
Sexual Syphilis
Trauma Injury
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

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