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==Historical Perspective==
==Historical Perspective==
*In 1914, Dr. Simmonds was the first one to describe the hypothryoidism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.  
*In 1914, Dr. Simmonds was the first one to describe the hypopituitarism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.<ref name="pmid17467517">{{cite journal| author=Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E| title=Hypopituitarism. | journal=Lancet | year= 2007 | volume= 369 | issue= 9571 | pages= 1461-70 | pmid=17467517 | doi=10.1016/S0140-6736(07)60673-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17467517  }} </ref>
*In 1950, Dr. Yalow and Berson discovered the radioimmunoassay which helped in measurement of the pituitary hormones after the diagnosis was only based on the signs and symptoms presented with the patients.<ref name="pmid441860">{{cite journal| author=Prozesky OW| title=Measles vaccination. | journal=S Afr Med J | year= 1979 | volume= 55 | issue= 7 | pages= 236 | pmid=441860 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=441860  }} </ref>
*In 1973, combined stimulation tests of the hormones insulin, GnRH and TRH were performed for the first time to assess the pituitary gland funciton.<ref name="pmid4202260">{{cite journal| author=Harsoulis P, Marshall JC, Kuku SF, Burke CW, London DR, Fraser TR| title=Combined test for assessment of anterior pituitary function. | journal=Br Med J | year= 1973 | volume= 4 | issue= 5888 | pages= 326-9 | pmid=4202260 | doi= | pmc=1587416 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4202260  }} </ref>
*Through the 20th and 21st centuries, causes of the hypopituitarism were being described.


==References==
==References==

Revision as of 15:33, 7 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Historical Perspective

  • In 1914, Dr. Simmonds was the first one to describe the hypopituitarism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.[1]
  • In 1950, Dr. Yalow and Berson discovered the radioimmunoassay which helped in measurement of the pituitary hormones after the diagnosis was only based on the signs and symptoms presented with the patients.[2]
  • In 1973, combined stimulation tests of the hormones insulin, GnRH and TRH were performed for the first time to assess the pituitary gland funciton.[3]
  • Through the 20th and 21st centuries, causes of the hypopituitarism were being described.

References

  1. Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E (2007). "Hypopituitarism". Lancet. 369 (9571): 1461–70. doi:10.1016/S0140-6736(07)60673-4. PMID 17467517.
  2. Prozesky OW (1979). "Measles vaccination". S Afr Med J. 55 (7): 236. PMID 441860.
  3. Harsoulis P, Marshall JC, Kuku SF, Burke CW, London DR, Fraser TR (1973). "Combined test for assessment of anterior pituitary function". Br Med J. 4 (5888): 326–9. PMC 1587416. PMID 4202260.

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