Hypopharyngeal cancer

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cancer of the throat is cancer of the vocal cords, voice box (larynx), or other areas of the throat.

Epidemiology and Demographics

  • Most cancers of the throat develop in adults older than 50.
  • Men are 10 times more likely than women to develop throat cancers.

Risk Factors

  • Smoking
  • Alcohol
  • Tobacco use

Natural History , Complications and Prognosis

Complications

  • Airway obstruction
  • Difficulty swallowing
  • Pain during swallowing
  • Disfigurement of the neck or face
  • Hardening of the skin of the neck
  • Loss of voice and speaking ability
  • Spread of the cancer to other body areas (metastasis)

Prognosis

Throat cancers can be cured in 90% of patients if detected early. If the cancer has spread to surrounding tissues or lymph nodes in the neck, 50 - 60% of patients can be cured. If the cancer has spread (metastasized) to parts of the body outside the head and neck, the cancer is not curable and treatment is aimed at prolonging and improving quality of life. After treatment, patients generally need therapy to help with speech and swallowing. A small percentage of patients (5%) will not be able to swallow and will need to be fed through a feeding tube

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