|euchromatic histone-lysine N-methyltransferase 1|
|Locus||Chr. 9 |
Histone methyltransferases (HMT) are enzymes, histone-lysine N-methyltransferase and histone-arginine N-methyltransferase, which catalyze the transfer of one to three methyl groups from the cofactor S-Adenosyl methionine to lysine and arginine residues of histone proteins. These proteins often contain an SET (Su(var)3-9, Enhancer of Zeste, Trithorax) domain, however the recently discovered HMT Dot1 lacks the characteristic SET domain.
- Histone-Modifying Enzymes
- Histone acetyltransferase
- Histone deacetylase
- RNA polymerase control by chromatin structure
Methylated histones can either repress or activate transcription as different experimental findings suggest.
- Histone-Lysine+N-Methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
- Protein-Arginine+N-Methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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