Hepatocellular adenoma MRI: Difference between revisions

Jump to navigation Jump to search
(Mahshid)
Line 6: Line 6:


==MRI==
==MRI==
 
* The MR imgaing findings of hepatocellualar adenoma include;
* On T1-weighted MR images, hepatocellular adenomas have been variously described as hyperintense, isointense, and hypointense lesions.
* From hyperintense to mildly hypointense relative to liver tissue on T1 weighted images. This heterogeneous appearance results from areas of high intensity due to fat and acute hemorrhage and low signal intensity area corresponding to necrosis or old hemorrhage or calcifications.
 
* The hepatocellular adenoma in T2 weighted images are predominantly hyperintense relative to liver, although in the presence of necrosis and hemorrhage they can be heterogeneous with hyper and hypo attenuating signal.
* It has been reported that 47%–74% of hepatocellular adenomas are predominantly hyperintense relative to liver on T2-weighted images; this is due to prolonged T2 and is consistent with findings in other hepatic tumors.
* Dynamic postgodalinium show intense arterial phase enhancement with isointensity on portal phase and delayed images.
 
* Hepatocellular adenoma do not have a central scar so if a central scar enhances after godalinium is administered, the diagnosis of focal nodular hyperplasia is strongly favored.
* Some lesions are hypointense and isointense on T2-weighted images.
* A central scar has never been reported in hepatocellular adenomas.
 
* With the injection of hepatocellular specific contrast agent, godalinium benzyloxypropionictetraacetate (Gd-BOTA) there is usually no significant uptake.
* Most lesions are heterogeneous, demonstrating a combination of hyper- and hypointensity on T2-weighted images relative to hemorrhage and necrosis.
 
*Dynamic gadolinium-enhanced gradient-echo MR imaging, like dynamic CT, can be used to demonstrate early arterial enhancement that reflects the presence of subcapsular feeding vessels.
 
*Adenomas usually do not show uptake of superparamagnetic iron oxide particles, resulting in decreased signal intensity on T2-weighted images.
 
*After injection of a hepatocellular-specific contrast agent such as gadolinium benzyloxypropionictetraacetate (Gd-BOPTA) there is usually no substantial uptake.
<Gallery>
<Gallery>
Axial_T1_out_of_phase_hepatic_adenoma.jpg|liver MRI show a large, subtle T2 hyperintense, well defined rounded lesion in the liver which demonstrates homogenous signal loss on T1 opposed phase scans.
Axial_T1_out_of_phase_hepatic_adenoma.jpg|liver MRI show a large, subtle T2 hyperintense, well defined rounded lesion in the liver which demonstrates homogenous signal loss on T1 opposed phase scans.

Revision as of 20:31, 8 January 2019

Hepatocellular adenoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hepatocellular adenoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Hepatocellular adenoma MRI On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hepatocellular adenoma MRI

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hepatocellular adenoma MRI

CDC on Hepatocellular adenoma MRI

Hepatocellular adenoma MRI in the news

Blogs on Hepatocellular adenoma MRI

Directions to Hospitals Treating Hepatocellular adenoma

Risk calculators and risk factors for Hepatocellular adenoma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]Nawal Muazam M.D.[3]

Overview

MRI

  • The MR imgaing findings of hepatocellualar adenoma include;
  • From hyperintense to mildly hypointense relative to liver tissue on T1 weighted images. This heterogeneous appearance results from areas of high intensity due to fat and acute hemorrhage and low signal intensity area corresponding to necrosis or old hemorrhage or calcifications.
  • The hepatocellular adenoma in T2 weighted images are predominantly hyperintense relative to liver, although in the presence of necrosis and hemorrhage they can be heterogeneous with hyper and hypo attenuating signal.
  • Dynamic postgodalinium show intense arterial phase enhancement with isointensity on portal phase and delayed images.
  • Hepatocellular adenoma do not have a central scar so if a central scar enhances after godalinium is administered, the diagnosis of focal nodular hyperplasia is strongly favored.
  • A central scar has never been reported in hepatocellular adenomas.
  • With the injection of hepatocellular specific contrast agent, godalinium benzyloxypropionictetraacetate (Gd-BOTA) there is usually no significant uptake.

References


Template:WikiDoc Sources