Heparin-induced thrombocytopenia natural history, complications and prognosis
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Heparin-induced thrombocytopenia |
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Differentiating Heparin-induced thrombocytopenia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; {shyam}}
Overview
Natural History
Complications
Complications of HIT are most thrombotic in nature. These can be quite devastating, which high morbidity and mortality.
- Acute limb ischemia[1]: This can sometimes require limb amputation to prevent further tissue damage and sepsis from the thrombotic arm or leg.
- Pulmonary embolism[1]
- Stroke[1]
- Skin necrosis[1]
Prognosis
Reference
- ↑ 1.0 1.1 1.2 1.3 Linkins LA, Dans AL, Moores LK, Bona R, Davidson BL, Schulman S; et al. (2012). "Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e495S–e530S. doi:10.1378/chest.11-2303. PMC 3278058. PMID 22315270.