Hemophilia natural history, complications and prognosis: Difference between revisions
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==Complications== | ==Complications== | ||
Major complications include | Major complications include | ||
*[[Hemarthrosis]] | *[[Hemarthrosis]]: Bleeding into the joints leads to hemophilic arthropathy. Hemorrhage most often occurs in the synovial joints. In descending order, the knee, ankle, elbow, shoulder, and hip are involved. | ||
*[[Hemorrhage]] | *[[Hemorrhage]] | ||
*[[Gastrointestinal bleeding]] | *[[Gastrointestinal bleeding]] | ||
*[[Menorrhagia]] | *[[Menorrhagia]] | ||
* The clinical and radiologic features of patients with classic hemophilia and Christmas disease are virtually identical. | |||
* Repetitive bleeding into the musculoskeletal system is the most common complication of both conditions. | |||
* Bleeding into muscles causes joint contractures | |||
* Bleeding into bone and adjacent soft tissues results in osseous and soft-tissue pseudotumors. | |||
==Prognosis== | ==Prognosis== |
Revision as of 14:44, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
Major complications include
- Hemarthrosis: Bleeding into the joints leads to hemophilic arthropathy. Hemorrhage most often occurs in the synovial joints. In descending order, the knee, ankle, elbow, shoulder, and hip are involved.
- Hemorrhage
- Gastrointestinal bleeding
- Menorrhagia
- The clinical and radiologic features of patients with classic hemophilia and Christmas disease are virtually identical.
- Repetitive bleeding into the musculoskeletal system is the most common complication of both conditions.
- Bleeding into muscles causes joint contractures
- Bleeding into bone and adjacent soft tissues results in osseous and soft-tissue pseudotumors.