Hemophagocytic lymphohistiocytosis natural history, complications and prognosis

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Hemophagocytic lymphohistiocytosis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

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Differentiating Hemophagocytic lymphohistiocytosis from other Diseases

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Natural History

Complications

Prognosis

  • Secondary HLH in some individuals may be self-limited because patients are able to fully recover after having received only supportive medical treatment. However, long-term remission without the use of cytotoxic and immune-suppressive therapies is unlikely in the majority of adults with HLH and in those with CNS involvement.
  • Without treatment, most people with familial hemophagocytic lymphohistiocytosis survive only a few months.

References

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