Hemochromatosis physical examination: Difference between revisions
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* [[Erectile dysfunction]] and [[hypogonadism]] | * [[Erectile dysfunction]] and [[hypogonadism]] | ||
* Congestive [[heart failure]], [[arrhythmia]]s or [[pericarditis]] | * Congestive [[heart failure]], [[arrhythmia]]s or [[pericarditis]] | ||
* [[Deafness]]<ref name=Jones_1983>{{cite journal |author=Jones H, Hedley-Whyte E |title=Idiopathic hemochromatosis (IHC): dementia and ataxia as presenting signs |journal=Neurology |volume=33 |issue=11 |pages=1479-83 |year=1983 |pmid=6685241}}</ref> | * [[Deafness]]<ref name="Jones_1983">{{cite journal |author=Jones H, Hedley-Whyte E |title=Idiopathic hemochromatosis (IHC): dementia and ataxia as presenting signs |journal=Neurology |volume=33 |issue=11 |pages=1479-83 |year=1983 |pmid=6685241}}</ref> | ||
*[[Dyskinesia]]s, including [[Parkinsonian]] symptoms<ref name=Costello_2004>{{cite journal |author=Costello D, Walsh S, Harrington H, Walsh C |title=Concurrent hereditary haemochromatosis and idiopathic Parkinson's disease: a case report series |journal=J Neurol Neurosurg Psychiatry |volume=75 |issue=4 |pages=631-3 |year=2004 |pmid=15026513}}</ref><ref name=Jones_1983 /><ref name=Nielsen_1995>{{cite journal |author=Nielsen J, Jensen L, Krabbe K |title=Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome |journal=J Neurol Neurosurg Psychiatry |volume=59 |issue=3 |pages=318-21 |year=1995 |pmid=7673967}}</ref> | *[[Dyskinesia]]s, including [[Parkinsonian]] symptoms<ref name="Costello_2004">{{cite journal |author=Costello D, Walsh S, Harrington H, Walsh C |title=Concurrent hereditary haemochromatosis and idiopathic Parkinson's disease: a case report series |journal=J Neurol Neurosurg Psychiatry |volume=75 |issue=4 |pages=631-3 |year=2004 |pmid=15026513}}</ref><ref name="Jones_1983" /><ref name="Nielsen_1995">{{cite journal |author=Nielsen J, Jensen L, Krabbe K |title=Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome |journal=J Neurol Neurosurg Psychiatry |volume=59 |issue=3 |pages=318-21 |year=1995 |pmid=7673967}}</ref> | ||
* Dysfunction of certain [[endocrine organs]]: | * Dysfunction of certain [[endocrine organs]]: | ||
** [[Pancreas|Pancreatic gland]], as above, manifesting as [[diabetes]] | ** [[Pancreas|Pancreatic gland]], as above, manifesting as [[diabetes]] | ||
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Males are usually diagnosed after their forties, and women about a decade later, owing to regular iron loss by [[menstruation]] (which ceases in [[menopause]]). Cases of [[iron]] overload have been found in young children as well. | Males are usually diagnosed after their forties, and women about a decade later, owing to regular iron loss by [[menstruation]] (which ceases in [[menopause]]). Cases of [[iron]] overload have been found in young children as well. | ||
{| class="wikitable" | |||
!System involved | |||
!Organs | |||
!Symptom | |||
!Signs | |||
!Mechanisum | |||
! | |||
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| rowspan="2" |Nervous system | |||
|PNS | |||
|Parastheisa | |||
Loss of motor control | |||
|Loss of two point discrimination | |||
Hyporeflaxia decreased power | |||
|Axonal sensory motor polyneuropathy | |||
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|- | |||
|CNS | |||
|Abnormal gait | |||
Dementia | |||
|Dyskinesias(parkinsonian syndrome Multiple sclerosis) | |||
cognitive decline | |||
|Deposition of iron in basal ganglia | |||
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==References== | ==References== | ||
Revision as of 16:05, 4 December 2017
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Hemochromatosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hemochromatosis physical examination On the Web |
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American Roentgen Ray Society Images of Hemochromatosis physical examination |
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Risk calculators and risk factors for Hemochromatosis physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Physical Examination
- Erectile dysfunction and hypogonadism
- Congestive heart failure, arrhythmias or pericarditis
- Deafness[1]
- Dyskinesias, including Parkinsonian symptoms[2][1][3]
- Dysfunction of certain endocrine organs:
- Pancreatic gland, as above, manifesting as diabetes
- Adrenal gland (leading to adrenal insufficiency)
- Parathyroid gland (leading to hypocalcaemia)
- Pituitary gland
- Testes or ovary (leading to hypogonadism)
- A darkish color to the skin (see pigmentation, hence its name Diabete bronze )
Males are usually diagnosed after their forties, and women about a decade later, owing to regular iron loss by menstruation (which ceases in menopause). Cases of iron overload have been found in young children as well.
| System involved | Organs | Symptom | Signs | Mechanisum | |
|---|---|---|---|---|---|
| Nervous system | PNS | Parastheisa
Loss of motor control |
Loss of two point discrimination
Hyporeflaxia decreased power |
Axonal sensory motor polyneuropathy | |
| CNS | Abnormal gait
Dementia |
Dyskinesias(parkinsonian syndrome Multiple sclerosis)
cognitive decline |
Deposition of iron in basal ganglia | ||
References
- ↑ 1.0 1.1 Jones H, Hedley-Whyte E (1983). "Idiopathic hemochromatosis (IHC): dementia and ataxia as presenting signs". Neurology. 33 (11): 1479–83. PMID 6685241.
- ↑ Costello D, Walsh S, Harrington H, Walsh C (2004). "Concurrent hereditary haemochromatosis and idiopathic Parkinson's disease: a case report series". J Neurol Neurosurg Psychiatry. 75 (4): 631–3. PMID 15026513.
- ↑ Nielsen J, Jensen L, Krabbe K (1995). "Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome". J Neurol Neurosurg Psychiatry. 59 (3): 318–21. PMID 7673967.