Hemochromatosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

History and Symptoms

[1][2][3]

  • Early indications of hemochromatosis are often like those of other diseases and include the following symptoms:
  • As iron builds up in the body organs, hemochromatosis may also produce the following symptoms:
  • Loss of menstrual periods or early menopause
  • Loss of sex drive (libido) or impotence
  • Loss of body hair
  • Shortness of breath
  • As the disease progresses, hemochromatosis may cause the following more serious problems:
  • Arthritis
  • Abdominal pain that does not go away
  • Severe fatigue (feeling extremely tired and having a lack of energy)
  • Heart failure symptoms
  • Gray-colored or bronze-colored skin
  • Deafness[4]
  • A darkish color to the skin (see pigmentation, hence its name Diabete bronze when it was first described by Armand Trousseau in 1865)

References

  1. Iron Overload and Hemochromatosis Centers for Disease Control and Prevention
  2. Hemochromatosis National Digestive Diseases Information Clearinghouse, National Institutes of Health, U.S. Department of Health and Human Services
  3. Hemochromatosis-Signs and Symptoms Mayo Foundation for Medical Education and Research (MFMER)
  4. Jones H, Hedley-Whyte E (1983). "Idiopathic hemochromatosis (IHC): dementia and ataxia as presenting signs". Neurology. 33 (11): 1479–83. PMID 6685241.

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