Helper dependent virus: Difference between revisions
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Latest revision as of 15:52, 9 August 2012
Overview
A helper dependent virus also termed a gutless virus is a synthetic viral vector dependent on the assistance of a helper virus in order to replicate. Since the genome of the gutless virus does not include genes encoding the enzymes required to replicate, it is deemed safe for use in gene therapy since an infection cannot occur except in the presence of a suitable helper virus.