Hand-foot-and-mouth disease history and symptoms

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

It is characterized by fever, sores in the mouth, and a rash with blisters. HFMD begins with a mild fever, poor appetite, malaise ("feeling sick"), and frequently a sore throat.

History

Specific areas of focus when obtaining a history from the patient include history of:

Symptoms

Symptoms of hand-foot and mouth disease include:[1]

  • Fever
  • Headache
  • Loss of appetite
  • Rash with very small blisters on hands, feet, and diaper area; may be tender or painful if pressed
    • One or 2 days after the fever begins, painful sores develop in the mouth.
    • They begin as small red spots that blister and then often become ulcers.
    • They are usually located on the tongue, gums, and inside of the cheeks.
    • The skin rash develops over 1 to 2 days with flat or raised red spots, some with blisters.
    • The rash does not itch, and it is usually located on the palms of the hands and soles of the feet. It may also appear on the buttocks.
    • A person with HFMD may have only the rash or the mouth ulcers.
  • Sore throat
  • Ulcers in the throat (including tonsils), mouth, and tongue

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