Hamartoma classification: Difference between revisions

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* Hypothalamic hamartoma
* Hypothalamic hamartoma

Revision as of 16:23, 10 September 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Hamartomas may be classified into different types based on their location, such as: lung (most common), heart, hypothalamus, kidneys, or spleen. Other classifications can consider lesion class, dividing hamartomas into 4 different categories, such as: bone-forming, cartilage-forming, fiber-forming, and benign non–matrix-forming.[1]

Classification

Location

Based on the location, hamartomas can be classified into the following types:

Location Type
Hypothalamus and

tuber cinereum

  • Hypothalamic hamartoma
CNS
    • Neurofibromatosis in von Recklinghausen disease
    • Neuroepithelial cells in tuberous sclerosis
Lung
  • Endobronchial pulmonary hamartoma
  • Parenchymal pulmonary hamartoma
  • Bronchial hamartoma
Heart
  • Rhabdomyoma
Kidneys
  • Angiomyolipoma
Spleen
  • Splenic hamartoma
Skin
    • Melanocytic nevi
  • Lung
    • Endobronchial pulmonary hamartoma
    • Parenchymal pulmonary hamartoma
  • Heart
    • Rhabdomyoma
  • Hypothalamus
    • Hypothalamic hamartoma
  • Kidneys
    • Angiomyolipoma
  • Spleen
    • Splenic hamartoma

Lesion class

Based on the lesion class, hamartomas can be classified into the following types:

  • Bone-forming tumors
  • Cartilage-forming tumors
  • Fiber-forming tumors
    • Nonossifying fibroma
    • Fibrous dysplasia
    • Mazabraud syndrome
  • Benign non–matrix-forming tumors

References

  1. Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. Elsevier Health Sciences; 2012.


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