Hamartoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

CT scan is the imaging modality of choice for the diagnosis of hamartoma. On CT scan, hamartoma is characterized by focal collections of fat, a lesion with a smooth edge, and collections of fat alternating with foci of calcification.[1][2]

CT

  • On computed tomography, common findings of pulmonary hamartoma, include:[1][2]
  • Isodense or hypodense solid masses
  • Heterogeneous contrast enhancement relative to adjacent normal parenchyma
  • Presence of fat in a well circumscribed solitary pulmonary nodule which does not demonstrate significant growth
  • The fat components may be localized or generalized within the nodule and will typically have a Haunsfield measurement of -40 to -120 HU
  • Calcification is typically dispersed in the form of multiple clumps throughout the lesion in a popcorn configuration
  • On computed tomography, spleen hamartoma findings, include:[3]
  • Isodense or hypodense solid masses
  • Heterogeneous contrast enhancement relative to adjacent normal parenchyma
  • On computed tomography, common findings of renal hamartoma, include:[4]
  • Lesions involve the cortex and demonstrate macroscopic fat (less than -20 HU)
  • Small renal hamartomas volume averaging may make differentiation from a small cyst difficult
  • Renal hamartomas are fat-poor
  • Calcification is rare
  • On computed tomography, common findings of hypothalamic hamartoma, include:[5]
  • Iso-attenuating nodule of soft-tissue
  • Calcification is rare
  • There is no contrast enhancement

Gallery

References

  1. 1.0 1.1 Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ (2002). "Fat-containing lesions of the chest". Radiographics. 22 Spec No: S61–78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. PMID 12376601.
  2. 2.0 2.1 Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188
  3. Soto-Medina CA, Mier-Escurra EA, Treviño-Garza F, Ripa-Galván P (2014). "[Splenic hamartoma. Case report]". Cirugía Y Cirujanos (in Spanish; Castilian). 82 (3): 328–31. PMID 25238476.
  4. Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.
  5. Fenoglio KA, Wu J, Kim do Y, Simeone TA, Coons SW, Rekate H, Rho JM, Kerrigan JF (2007). "Hypothalamic hamartoma: basic mechanisms of intrinsic epileptogenesis". Seminars in Pediatric Neurology. 14 (2): 51–9. doi:10.1016/j.spen.2007.03.002. PMID 17544947.


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