Hamartoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

CT scan may be helpful in the diagnosis of hamartoma. Findings on CT scan suggestive of hamartoma include smooth edge, focal collections of fat, or collections of fat alternating with foci of calcification.[1][2]

CT

On computed tomography, hamartomas appear as isodense or hypodense solid masses and demonstrate heterogeneous contrast enhancement relative to adjacent normal parenchyma. The reported prevalence of calcification in hamartomas on CT varies from 5 to 50% while fat may be identified in up to 60% of hamartomas at CT. The fat components may be localized or generalized within the nodule.[1]

Fat can be recognised by comparing it to subcutaneous fat, and will typically have a Haunsfield measurement of -40 to -120 HU. Presence of fat in a well circumscribed solitary pulmonary nodule which does not demonstrate significant growth is essentially pathognomonic of a pulmonary hamartoma and no further investigations are required. Unfortunately fat can only be identified in 60% of lesions. Thin section CT is therefore essential to avoid missing small foci of fat. Calcification is typically dispersed in the form of multiple clumps throughout the lesion in a popcorn configuration.[2]

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References

  1. 1.0 1.1 Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ (2002). "Fat-containing lesions of the chest". Radiographics. 22 Spec No: S61–78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61. PMID 12376601.
  2. 2.0 2.1 Brant WE, Helms CA.(2007) Fundamentals of diagnostic radiology. Lippincott Williams & Wilkins.ISBN:0781765188


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