H1FNT: Difference between revisions

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(New page: {{protein | Name = H1 histone family, member N, testis-specific | caption = | image = | width = | HGNCid = 24893 | Symbol = H1FNT | AltSymbols = HANP1, H1T2 | EntrezGene = 341567 | OMIM = ...)
 
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{{protein
{{infobox protein
| Name = H1 histone family, member N, testis-specific
| Name = H1 histone family, member N, testis-specific
| caption =
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{{SI}}
'''H1 histone family, member N, testis-specific''' is a member of the [[histone]] family of nuclear [[protein]]s which are a component of [[chromatin]].  In humans, this protein is encoded by the ''H1FNT'' gene.<ref name="pmid15710904">{{cite journal  |vauthors=Martianov I, Brancorsini S, Catena R, etal | title = Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 8 | pages = 2808–13 |date=February 2005 | pmid = 15710904 | pmc = 549447 | doi = 10.1073/pnas.0406060102 | url = | issn = }}</ref>
{{EH}}


'''H1 histone family, member N, testis-specific''' is a member of the [[histone]] family of nuclear [[protein]]s which are a component of [[chromatin]].  In humans, this protein is encoded by the ''H1FNT'' gene.<ref name="pmid15710904">{{cite journal | author = Martianov I, Brancorsini S, Catena R, ''et al'' | title = Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 8 | pages = 2808–13 | year = 2005 | month = February | pmid = 15710904 | pmc = 549447 | doi = 10.1073/pnas.0406060102 | url = | issn = }}</ref>
The H1FNT protein is essential for nuclear formation in [[spermatozoa]], and is involved in the replacement of histones with [[protamine]]s during [[spermiogenesis]].<ref name="pmid16533358">{{cite journal |vauthors=Tanaka H, Matsuoka Y, Onishi M, Kitamura K, Miyagawa Y, Nishimura H, Tsujimura A, Okuyama A, Nishimune Y | title = Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein | journal = International Journal of Andrology | volume = 29 | issue = 2 | pages = 353–9 |date=April 2006 | pmid = 16533358 | doi = 10.1111/j.1365-2605.2005.00600.x | url = | issn = }}</ref>
 
The H1FNT protein is essential for nuclear formation in [[spermatozoa]], and is involved in the replacement of histones with [[protamine]]s during [[spermiogenesis]].<ref name="pmid16533358">{{cite journal | author = Tanaka H, Matsuoka Y, Onishi M, Kitamura K, Miyagawa Y, Nishimura H, Tsujimura A, Okuyama A, Nishimune Y | title = Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein | journal = International journal of andrology | volume = 29 | issue = 2 | pages = 353–9 | year = 2006 | month = April | pmid = 16533358 | doi = 10.1111sj.1365-2605.2005.00600.x | url = | issn = }}</ref>


==References==
==References==
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* {{MeshName|H1FNT+protein,+human}}
* {{MeshName|H1FNT+protein,+human}}


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Latest revision as of 07:05, 28 August 2018

H1 histone family, member N, testis-specific
Identifiers
SymbolH1FNT
Alt. symbolsHANP1, H1T2
Entrez341567
HUGO24893
RefSeqNM_181788
UniProtQ75WM6
Other data
LocusChr. 12 q13.11

H1 histone family, member N, testis-specific is a member of the histone family of nuclear proteins which are a component of chromatin. In humans, this protein is encoded by the H1FNT gene.[1]

The H1FNT protein is essential for nuclear formation in spermatozoa, and is involved in the replacement of histones with protamines during spermiogenesis.[2]

References

  1. Martianov I, Brancorsini S, Catena R, et al. (February 2005). "Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis". Proceedings of the National Academy of Sciences of the United States of America. 102 (8): 2808–13. doi:10.1073/pnas.0406060102. PMC 549447. PMID 15710904.
  2. Tanaka H, Matsuoka Y, Onishi M, Kitamura K, Miyagawa Y, Nishimura H, Tsujimura A, Okuyama A, Nishimune Y (April 2006). "Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein". International Journal of Andrology. 29 (2): 353–9. doi:10.1111/j.1365-2605.2005.00600.x. PMID 16533358.

External links