Guillain-Barré syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]

Overview

Nerve conduction study may show prolonged distal latencies, conduction slowing, conduction block, and temporal dispersion of compound action potential in demyelinating cases. Forced vital capacities also help in taking decisions regarding ventilators .

Other Diagnostic Studies

• Nerve conduction studies and needle electromyography may be helpful in the diagnosis of Guillain Barre syndrome and differentiating various sub types.

• Findings diagnostic of Guillain Barre syndrome include:
  • In demyelinating forms:
    • Reduced conduction velocity of motor nerves.
    • Increased distal motor latency.
    • increased latency of F wave.
    • conduction block
    • Temporal scattering
  • In axonal forms:
    • Reduced amplitude of distal motor and/or sensory nerve impulses.
    • Conduction block of motor nerves.