Goodpasture disease: Difference between revisions

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{{SK}} Anti-GBM nephritis with pulmonary hemorrhage; antiglomerular basement membrane disease; Goodpasture’s syndrome
{{SK}} Anti-GBM nephritis with pulmonary hemorrhage; antiglomerular basement membrane disease; Goodpasture’s syndrome
== Treatment ==
Like many autoimmune diseases, Goodpasture’s syndrome responds well to treatment with [[corticosteroid]]s and [[immunosuppressant]]s.  These drugs dampen the body's normal immune response.  A serious side effect of this is that the patient may become more susceptible to infections. The concentration of anti-GBM antibodies in the blood may be reduced by [[apheresis]] to remove blood plasma and its replacement with an isotonic salt and protein solution. This course of treatment usually lasts between three and six months.
[[Antibiotic]] treatment of lung infection and stopping smoking may also help to reduce lung haemorrhaging.
However, none of these can reverse permanent kidney damage and so for patients who have suffered this, renal [[organ transplant|transplant]] once the disease has subsided may be the only option.
== See also ==
== See also ==



Revision as of 18:42, 24 September 2012

Goodpasture disease
ICD-10 M31.0 (ILDS M31.010)
ICD-9 446.21
OMIM 233450
DiseasesDB 5363
MedlinePlus 142
MeSH D019867

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Synonyms and keywords: Anti-GBM nephritis with pulmonary hemorrhage; antiglomerular basement membrane disease; Goodpasture’s syndrome

See also

HLA-DR#DR2

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GBM antibodies: immunofluorescence image

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